Recombinant Rat Gap junction gamma-1 protein (Gjc1), partial

中文名稱：

大鼠Gjc1重組蛋白
貨號：

CSB-YP009458RA1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Gjc1重組蛋白
貨號：

CSB-EP009458RA1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Gjc1重組蛋白
貨號：

CSB-EP009458RA1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Gjc1重組蛋白
貨號：

CSB-BP009458RA1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Gjc1重組蛋白
貨號：

CSB-MP009458RA1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gjc1
Uniprot No.：

A4GG66
別名：

Gjc1; Gja7; Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
基因功能參考文獻：
1. The results of the present study revealed that during memory consolidation in a passive avoidance paradigm, a rapid upregulation of Cx45 mRNAs level occurs in the hippocampus, which declines to the control level by 24 h after training. PMID: 27913256
2. The absence of Cx43/Cx45 hemichannels in skeltal muscles cells greatly attenuates the inflammasome activation and muscle atrophy. PMID: 24043768
3. Findings demonstrate that overexpression of connexin 45 and subsequent formation of heteromeric connexin 45/connexin 43 gap junction channels in HCN4 expressing MSCs can improve their function as cardiac biological pacemakers in vitro. PMID: 20819514
4. data suggests that connexin 45 and ZO-1 directly interact in osteoblastic cells (ROS/Cx45) [ZO-1] PMID: 12064590
5. Cx45 mRNAs are localized in neuronal cells in both developing and adult rat brain. PMID: 14622215
6. Analysis of Cx45 RNA expression in various rat tissues and cultured cell lines revealed that the transcripts composed of either E1a, E2, and E3 (i.e., E1a/2/3) or of E1b, E2, and E3 (E1b/2/3) sequences are both ubiquitously expressed. PMID: 17328669
7. Report regulation of connexin 45 gene expression during skeletal muscle regeneration in the adult rat. PMID: 19129462
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亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
蛋白家族：

Connexin family, Gamma-type subfamily
組織特異性：

Ubiquitous.
數據庫鏈接：

KEGG: rno:266706

STRING: 10116.ENSRNOP00000066371

UniGene: Rn.195419