Recombinant Rat Dual specificity protein phosphatase 5 (Dusp5)

中文名稱：

大鼠Dusp5重組蛋白
貨號：

CSB-YP007257RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Dusp5重組蛋白
貨號：

CSB-EP007257RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Dusp5重組蛋白
貨號：

CSB-EP007257RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Dusp5重組蛋白
貨號：

CSB-BP007257RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Dusp5重組蛋白
貨號：

CSB-MP007257RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dusp5
Uniprot No.：

O54838
別名：

Dusp5Dual specificity protein phosphatase 5; EC 3.1.3.16; EC 3.1.3.48; MAP-kinase phosphatase CPG21
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-384
氨基酸序列

MKVTSLDGRR LRKMLRKEAE ARCVVLDCRP YLAFAASSVR GSLNVNLNSV VLRRARGGAV SARYVLADEA ARARLLQEGG GGVAAVVVLD QGSRHWQKLR EESAARVVLT SLLACLSAGP RVYFLKGGYE TFYSQYPECC VDAKPISQEK LEGERGLLSQ CGKPILSVAY RPAYDQGGPV EILPFLYLGS AYHASKCEFL ANLHITALLN VSRRTSEACT THLHYKWIPV EDSHTADISS HFQEAIDFID CVREEGGKVL VHCEAGVSRS PTICMAYLMK TKQFRLKEAF EYIKQRRSVV SPNFGFMGQL LQYESEILPS TPTPQPPSCQ GEAASSTFIG HLQTLSPDMQ GAYCTFPTSV LAPVPTHATV AELHRSPVAT ATSC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1.
基因功能參考文獻：
1. miR-32-5p promotes neuroinflammation and neuropathic pain development through regulation of Dusp5. PMID: 29108992
2. Dusp5 modulates myogenic reactivity and autoregulation in the cerebral circulation. PMID: 25397684
3. DUSP-5, native in cerebral arterial muscle cells, appears to regulate signaling of pressure-dependent myogenic cerebral arterial constriction, which is crucial for the maintenance of constant cerebral blood flow to the brain. PMID: 23172031
4. Intrauterine growth retardation affects hippocampal DUSP5 expression and epigenetic characteristics in a sex-specific manner. PMID: 21828247
亞細胞定位：

Nucleus.
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
數據庫鏈接：

KEGG: rno:171109

STRING: 10116.ENSRNOP00000018889

UniGene: Rn.10877