Recombinant Rat Corticosteroid-binding globulin (Serpina6)

中文名稱：

大鼠Serpina6重組蛋白
貨號：

CSB-YP021062RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Serpina6重組蛋白
貨號：

CSB-EP021062RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Serpina6重組蛋白
貨號：

CSB-EP021062RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Serpina6重組蛋白
貨號：

CSB-BP021062RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Serpina6重組蛋白
貨號：

CSB-MP021062RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Serpina6
Uniprot No.：

P31211
別名：

Serpina6; CbgCorticosteroid-binding globulin; CBG; Serpin A6; Transcortin
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-396
氨基酸序列

STNESSNS HRGLAPTNVD FAFNLYQRLV ALNPDKNTLI SPVSISMALA MVSLGSAQTQ SLQSLGFNLT ETSEAEIHQS FQYLNYLLKQ SDTGLEMNMG NAMFLLQKLK LKDSFLADVK QYYESEALAI DFEDWTKASQ QINQHVKDKT QGKIEHVFSD LDSPASFILV NYIFLRGIWE LPFSPENTRE EDFYVNETST VKVPMMVQSG SIGYFRDSVF PCQLIQMDYV GNGTAFFILP DQGQMDTVIA ALSRDTIDRW GKLMTPRQVN LYIPKFSISD TYDLKDMLED LNIKDLLTNQ SDFSGNTKDV PLTLTMVHKA MLQLDEGNVL PNSTNGAPLH LRSEPLDIKF NKPFILLLFD KFTWSSLMMS QVVNPA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
基因功能參考文獻：
1. levels and integrity of plasma CBG are biomarkers of the onset and severity of inflammation PMID: 27418032
2. It is most likely that CBG in the brain may be involved in the response to changing systemic glucocorticoid levels. PMID: 23279724
3. corticosteroid binding globulin PMID: 23141917
4. Food restriction induced higher corticosterone plasma concentration at both ages, but only in pups did CBG binding increase after short- and long-term treatments PMID: 19833863
5. multiple locations of corticosteroid binding globulin throughout the central nervous system suggest multiple functional properties, including neuroendocrine and neurohumoral functions PMID: 17467234
6. analysis of the structural basis for steroid transport and proteinase-triggered release of CBG PMID: 17644521
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亞細胞定位：

Secreted.
蛋白家族：

Serpin family
組織特異性：

Expressed by the liver; secreted in plasma.
數據庫鏈接：

KEGG: rno:299270

STRING: 10116.ENSRNOP00000012500

UniGene: Rn.2374