Recombinant Rat Ameloblastin (Ambn)

中文名稱：

Recombinant Rat Ameloblastin(Ambn)
貨號：

CSB-YP730811RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Ameloblastin(Ambn)
貨號：

CSB-EP730811RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Ameloblastin(Ambn)
貨號：

CSB-EP730811RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Ameloblastin(Ambn)
貨號：

CSB-BP730811RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Ameloblastin(Ambn)
貨號：

CSB-MP730811RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ambn
Uniprot No.：

Q62840
別名：

AmbnAmeloblastin; Amelin
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

27-422
氨基酸序列

VPAF PQQPGAQGMA PPGMASLSLE TMRQLGSLQG LNALSQYSRL GFGKALNSLW LHGLLPPHNS FPWIGPREHE TQQYEYSLPV HPPPLPSQPS LQPHQPGLKP FLQPTAATGV QVTPQKPGPH PPMHPGQLPL QEGELIAPDE PQVAPSENPP TPEVPIMDFA DPQFPTVFQI AHSLSRGPMA HNKVPTFYPG MFYMSYGANQ LNAPARIGFM SSEEMPGERG SPMAYGTLFP GYGGFRQTLR GLNQNSPKGG DFTVEVDSPV SVTKGPEKGE GPEGSPLQEA SPDKGENPAL LSQMAPGAHA GLLAFPNDHI PNMARGPAGQ RLLGVTPAAA DPLITPELAE VYETYGADVT TPLGDGEATM DITMSPDTQQ PPMPGNKVHQ PQVHNAWRFQ EP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the mineralization and structural organization of enamel.
基因功能參考文獻：
1. Fluoride could decrease ameloblast viability, induce ameloblast apoptosis via activating FasL/Fas signaling pathway, and reduce AMBN secretion. PMID: 27193486
2. Findings suggest a role for this protein in early bone formation and repair. PMID: 20854943
3. ameloblastin is expressed in osteoblasts and functions as a promoting factor for osteogenic differentiation via a novel pathway through the interaction between CD63 and integrin beta1 PMID: 21149578
4. exon 3a and 11 are potential alternative splicing sites, producing 4 types of ameloblastin mRNA, from which ameloblastin I and II could be translated PMID: 12803485
5. express[ed] during craniofacial bone development in rats PMID: 17184233
6. subpopulation of granules containing only AMBN could be responsible for augmenting its local concentration along secretory surfaces against which hydroxyapatite crystals actively elongate PMID: 18281204
7. AMBN promotes cell binding through the heparin binding sites and plays an important role in preventing odontogenic tumor development by suppressing cell proliferation and maintaining differentiation phenotype through Msx2, p21, and p27. PMID: 19648121
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Ameloblastin family
組織特異性：

Ameloblast-specific.
數據庫鏈接：

KEGG: rno:25376

STRING: 10116.ENSRNOP00000005003

UniGene: Rn.11370