Recombinant Pig Beta-defensin 1 (DEFB1)

^{In
Stock}

品名簡稱：

Recombinant Pig DEFB1 protein
貨號：

CSB-EP006662PI
說明書：

MSDS Datasheet
規格：

￥1836
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

DEFB1
Uniprot No.：

O62697
別名：

(BD-1)(Defensin, beta 1)
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

31.1 kDa
表達區域：

24-64aa
氨基酸序列

NIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal GST-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
基因功能參考文獻：
1. pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide. PMID: 23220638
2. Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line. PMID: 23065293
3. Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets PMID: 16552064
亞細胞定位：

Secreted. Membrane.
蛋白家族：

Beta-defensin family
數據庫鏈接：

KEGG: ssc:396819

STRING: 9823.ENSSSCP00000025388

UniGene: Ssc.16109