Recombinant Paxillin homolog 1 (pxl-1)

中文名稱：

秀麗隱桿線蟲pxl-1重組蛋白
貨號：

CSB-YP601006CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲pxl-1重組蛋白
貨號：

CSB-EP601006CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲pxl-1重組蛋白
貨號：

CSB-EP601006CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲pxl-1重組蛋白
貨號：

CSB-BP601006CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲pxl-1重組蛋白
貨號：

CSB-MP601006CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

pxl-1
Uniprot No.：

Q09476
別名：

pxl-1; tag-327; C28H8.6; Paxillin homolog 1
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-413
氨基酸序列

MPSDDRFADA VKPALEALLS DLQHTTEVLR RAHISDRRSQ SRDDFEQSYD LQGNLNTQSV SNGNITTSPY KRRSSEGKDY SKSQERIYEN ESRLNPPVYS RPSVQSLLSQ VEEPPIRASS SRKSLGPPSQ AQSYSDVRSN GRSPSRDPLH SDSMIGTMNG ELSSKHGVNT IPKGDCAACG KPIIGQVVIA LGKMWHPEHY TCCECGAELG QRPFFERNGR AFCEEDYHNQ FSPKCQGCHR AITDRCVSVM NKNFHIECFT CAECNQPFGE DGFHEKNGQT YCKRDFFRLF APKCNGCSQP ITSNFITALG THWHPDCFVC QHCGVSFNGA SFFEHNGAPL CERHYHESRG SICSQCRGAI NGRCVAAMGR KFHPEHFRCS YCNHQLTKGT FKEVDRRPFC HKCYNNTYAL TPA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for myofilament organization of the pharyngeal sarcomeres and for pharyngeal muscle contractions and hence for pharyngeal pumping. Together with lin-8, might be required for myofilament organization in the body wall muscles.
基因功能參考文獻：
1. a loss-of-function allele of pxl-1 shows that loss of paxillin leads to early larval arrested animals with paralyzed pharyngeal muscles and eventual lethality PMID: 21633109
亞細胞定位：

[Isoform a]: Cell junction, adherens junction. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Cell projection, podosome.; [Isoform c]: Cell projection, podosome.
蛋白家族：

Paxillin family
組織特異性：

Isoform a: Expressed in all 95 body wall muscle cells as well as in the pharyngeal muscle cells (at protein level). Isoform c: Expressed in the body wall muscle cells and in the pharyngeal muscle cells.
數據庫鏈接：

KEGG: cel:CELE_C28H8.6

STRING: 6239.C28H8.6a

UniGene: Cel.10786