Recombinant Neisseria meningitidis serogroup B Quinolinate synthase (nadA)

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中文名稱：

腦膜炎奈瑟菌血清組nadA重組蛋白
品名簡稱：

Recombinant Neisseria meningitidis serogroup B nadA protein
貨號：

CSB-EP878213NGG
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP878213NGG could indicate that this peptide derived from E.coli-expressed Neisseria meningitidis serogroup B (strain MC58) nadA.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP878213NGG could indicate that this peptide derived from E.coli-expressed Neisseria meningitidis serogroup B (strain MC58) nadA.
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

nadA
Uniprot No.：

Q9K105
別名：

nadA; NMB0394; Quinolinate synthase A; EC 2.5.1.72
種屬：

Neisseria meningitidis serogroup B (strain MC58)
蛋白長度：

Full Length
來源：

E.coli
分子量：

44.2 kDa
表達區域：

1-370aa
氨基酸序列

MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKKKDVFNGMGPA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
基因功能參考文獻：
1. Data show that a protective conformational epitope is located in the head of Neisserial adhesin A (NadA). PMID: 25404323
2. The prevalence and genetic diversity of pilE and nadA were investigated in the prevalent serogroups and clonal complexes of N. meningitidis isolated in China. PMID: 23290624
3. The authors demonstrate by reporter gene fusion assays that alterations of the FarR binding site within the nadA promoter are sufficient to induce transcription of nadA. PMID: 21292554
4. Our results suggest that NadA expression is under both stochastic and tight environmental-sensing regulatory control PMID: 20041170
5. NmFarR is a negative transcriptional regulator of the adhesin/invasin NadA. PMID: 19400792
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亞細胞定位：

Cytoplasm.
蛋白家族：

Quinolinate synthase A family, Type 1 subfamily
數據庫鏈接：

KEGG: nme:NMB0394

STRING: 122586.NMB0394