Recombinant Myoblast determination protein 1 homolog (hlh-1)

中文名稱：

秀麗隱桿線蟲hlh-1重組蛋白
貨號：

CSB-YP326026CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲hlh-1重組蛋白
貨號：

CSB-EP326026CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲hlh-1重組蛋白
貨號：

CSB-EP326026CXY-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲hlh-1重組蛋白
貨號：

CSB-BP326026CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲hlh-1重組蛋白
貨號：

CSB-MP326026CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

hlh-1
Uniprot No.：

P22980
別名：

hlh-1; B0304.1; Myoblast determination protein 1 homolog; MyoD protein 1; Helix-loop-helix protein 1
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區(qū)域：

1-324
氨基酸序列

MNTETSTQSA PSDTYDTSIY YNSSPRVTAN DITTLTSFAA PAPQVLDYAN TQYDIYRNQP AYYLPSYAPT APTTFYSDFA NFNVTRSQDF ASVPAVANSS DVKPIIIKQE KSTPNATELI IQSRVDSQHE DTTTSTAGGA GVGGPRRTKF VLSVDRRKAA TMRERRRLRK VNEAFEVVKQ RTCPNPNQRL PKVEILRSAI DYINNLERML QQAGKMTKIM EQNQHLQMTQ QINGAPPHDY VTSSHFASSS YNPENMFDDD DLTDSDDDRD HHKLGNAVDL RRRNSLDRLS RIVASIPNEE AMTDEQLLQP ANDVIDGEKK LEML
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in myogenesis, in cooperation with transcription factors unc-120 and hnd-1. Acts redundantly with fozi-1 to promote body wall muscle cell and coelomocyte specification in postembryonic mesoderm progenitors, probably through suppression of sem-2.
基因功能參考文獻：
1. We found that HLH-1-dependent myogenic conversion specifically induced the expression of putative HLH-1-regulated chaperones in differentiating muscle cells. Moreover, disrupting the putative HLH-1-binding sites on ubiquitously expressed daf-21(Hsp90) and muscle-enriched hsp-12.2(sHsp) promoters abolished their myogenic-dependent expressio PMID: 28036392
2. CeMyoD (HLH-1) is a myogenic regulatory factor that can convert almost all cells to a muscle-like fate, regardless of their lineage of origin. PMID: 15772130
3. findings demonstrate that UNC-120/SRF and HND-1/HAND act in concert with HLH-1 to regulate myogenesis PMID: 17142668
4. hlh-1 is indeed a direct target of PAL-1 in the posterior embryonic C. elegans muscle lineages, defining a novel in vivo binding site for this crucial developmental regulator PMID: 19261701
亞細胞定位：

Nucleus.
組織特異性：

Body wall muscle cells; in clonal muscle precursors, in a set of early embryonic blastomeres (the ms-granddaughters), and in six glial-like cells called GLRS.
數據庫鏈接：

KEGG: cel:CELE_B0304.1

STRING: 6239.B0304.1b

UniGene: Cel.6667