Recombinant Mouse Zinc finger protein 24 (Znf24)

中文名稱：

小鼠Znf24重組蛋白
貨號：

CSB-YP026606MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Znf24重組蛋白
貨號：

CSB-EP026606MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Znf24重組蛋白
貨號：

CSB-EP026606MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Znf24重組蛋白
貨號：

CSB-BP026606MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Znf24重組蛋白
貨號：

CSB-MP026606MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Znf24
Uniprot No.：

Q91VN1
別名：

Znf24; Hmcns; Zfp191; Zfp24; Zinc finger protein 24; Hypomyelinated CNS protein; Zinc finger protein 191; Zinc finger protein ZF-12
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-368
氨基酸序列

MSAQSVEEDS ILIIPNPDEE EKILRVKLEE DPDGEEGSSI SWNHLPDPEV FRQRFRQFGY QDSPGPREAV SQLRELCRLW LRPETHTKEQ ILELVVLEQF VAILPKELQT WVREHHPENG EEAVAVLEDL ESELDDPGQP VSLRRQKREV LVEEITSQED AQGLPSSELD AVENQLKWAS WELHSLRHCD DDATTENGAL APKQEMASAG ESHEGPGTLN IGVPQLFKYG ETCFPKGRFE RKRNPSRKKQ HICDECGKHF SQGSALILHQ RIHSGEKPYG CVECGKAFSR SSILVQHQRV HTGEKPYKCL ECGKAFSQNS GLINHQRIHT GEKPYECVQC GKSYSQSSNL FRHQRRHNAE KLLNVVKV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.
基因功能參考文獻：
1. ZFP191 played an essential role in aggressive proliferation and migration of vascular smooth muscle cells, which in turn facilitated intimal hyperplasia. PMID: 23755975
2. The loss of Zfp191 may suppress systemic inflammation by reducing these cytokine levels during lipopolysaccharide-induced endotoxic shock. PMID: 22183946
3. this study demonstrates that ZFP191 is required for the myelinating function of differentiated oligodendrocytes. PMID: 20080941
4. These data show that Zfp191 is indispensable for early embryonic development and cell proliferation. PMID: 17064688
5. the DNA-binding domain of Zfp191 can specifically bind to the TCAT repeat motif, and there is a cooperative effect among the target DNA's multiple binding sites PMID: 18685786
6. Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage. PMID: 19544452
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亞細胞定位：

Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
組織特異性：

Widely expressed with highest levels in heart, brain, liver, skeletal muscle, kidney and testis and very low levels in spleen and lung.
數據庫鏈接：

KEGG: mmu:59057

STRING: 10090.ENSMUSP00000064637

UniGene: Mm.417427