Recombinant Mouse Transmembrane protein 176B (Tmem176b), partial

中文名稱：

小鼠Tmem176b重組蛋白
貨號：

CSB-YP023758MO1
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Tmem176b重組蛋白
貨號：

CSB-EP023758MO1
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Tmem176b重組蛋白
貨號：

CSB-EP023758MO1-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tmem176b重組蛋白
貨號：

CSB-BP023758MO1
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tmem176b重組蛋白
貨號：

CSB-MP023758MO1
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tmem176b
Uniprot No.：

Q9R1Q6
別名：

Tmem176b; Clast1; Lr8; Transmembrane protein 176B; Protein LR8
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells.
基因功能參考文獻：
1. Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus. PMID: 27009467
2. Tmem176b induces the differentiation of myoblasts into an osteoblast lineage. PMID: 24085390
3. data identify the downregulation of Clast1/LR8 as a potentially important mechanism by which oncogenic Ras-mediated neoplastic transformation occurs PMID: 20550525
4. These data suggest that Tmem176B and Tmem176A associate to form multimers and restrain dendritic cell maturation. PMID: 20501748
5. The Clast1 gene is ubiquitously expressed in various organs of adult mice and is required for development of cerebellar granule cells. PMID: 16814752
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亞細胞定位：

Nucleus membrane; Multi-pass membrane protein.
蛋白家族：

TMEM176 family
組織特異性：

Ubiquitously expressed with higher expression in lung, liver, kidney and colon. Expressed in cerebellar granule cells.
數據庫鏈接：

KEGG: mmu:65963

STRING: 10090.ENSMUSP00000098972

UniGene: Mm.28385