Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2 (Art2b)

中文名稱：

Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2(Art2b)
貨號：

CSB-YP518580MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2(Art2b)
貨號：

CSB-EP518580MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2(Art2b)
貨號：

CSB-EP518580MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2(Art2b)
貨號：

CSB-BP518580MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2(Art2b)
貨號：

CSB-MP518580MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Art2b
Uniprot No.：

O35975
別名：

Art2b; Rt6-2; Rt6.2; T-cell ecto-ADP-ribosyltransferase 2; EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 2; ARTC2; Mono(ADP-ribosyl)transferase 2B; NAD(+) glycohydrolase; EC 3.2.2.5; T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2; T-cell differentiation marker Rt6 homolog 2; T-cell mono(ADP-ribosyl)transferase 2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

21-260
氨基酸序列

LAVPFMLDMA PNAFDDQYES CVEDMEKKAP QLLQEDFNMN EELKLEWEKA EINWKEIKNS TSYPAGFHDF HGTALVAYTG NLAIDFNRAV RDFKKSPDNF HYKAFHYYLT RAVQLLNDQG CSLVYRGTKV MFEYTGKGSV RFGQFSSSSL TKRVALSSNF FSNHGTLFII RTCLGVNIKE FSSFPREEEV LIPGYEVYHK VTAQNDNGYN EIFLDSPERK KSNFNCFYNG SAQTVNIDFS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has both NAD(+) glycohydrolase and ADP-ribosyltransferase activity.
基因功能參考文獻：
1. Data show that shedding of T Cell Ecto-ADP-ribosyltransferase ARTC2.2 alters its substrate profile. PMID: 26209623
2. Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. PMID: 20975043
3. ART2b is required for ADP-ribosylation of cell surface proteins PMID: 12370300
4. raft association focuses ART2.2 on specific targets that constitutively or inducibly associate with lipid rafts PMID: 15657180
5. Extracellular nicotinamide adenine dinucleotide (NAD)/ART2-dependent modification of the P2X7R purinergic receptor potentiates the ability of adenosine triphosphate (ATP) to activate the receptor, via a left shift in the ATP dose-response relationship. PMID: 19542469
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亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

Arg-specific ADP-ribosyltransferase family
組織特異性：

Expressed in spleen, intestine and thymus.
數據庫鏈接：

KEGG: mmu:11872

STRING: 10090.ENSMUSP00000065658

UniGene: Mm.57008