Recombinant Mouse Rab11 family-interacting protein 5 (Rab11fip5)

中文名稱：

小鼠Rab11fip5重組蛋白
貨號：

CSB-YP837136MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Rab11fip5重組蛋白
貨號：

CSB-EP837136MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Rab11fip5重組蛋白
貨號：

CSB-EP837136MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rab11fip5重組蛋白
貨號：

CSB-BP837136MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rab11fip5重組蛋白
貨號：

CSB-MP837136MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rab11fip5
Uniprot No.：

Q8R361
別名：

Rab11fip5; D6Ertd32e; Rip11; Rab11 family-interacting protein 5; Rab11-FIP5; Rab11-interacting protein Rip11
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-645
氨基酸序列

MALVRDPEPA AGSSRWLPTH VQVTVLRASG LRGKSSGAGS TSDAYTVIQV GREKYSTSVV EKTQGCPEWC EECSFELPPG ALDGLLRAQE ADAGPAPWAS GPNAACELVL TTMHRSLIGV DKFLGRATVA LDEVFRAGRA QHTQWYRLHS KPGKKEKERG EIQVTIQFTR NNLSASMFDL SMKDKPRSPF SKLKDRVKGK KKYDLESASA ILPSSALEDP ELGSLGKMGK AKGFFLRNKL RKSSLTQSNT SLGSDSTLSS TSGSLVYQGP GAELLTRSPS HSSWLSTEGG RDSIQSPKLL THKRTYSDEA SQLRAAPPRA LLELQGHLDG ASRSSLCVNG SHVYNEEPQP PLRHRSSISG PFPPSSSLHS VPPRSSEEGS RSSDDSWGRG SHGTSSSEAV PGQEELSKQA KGASCSGEEE GARLPEGKPV QVATPMVASS EAVAAEKDRK PRMGLFHHHH HQGLSRSEQG RRGSVGEKGS PSLGASPHHS STGEEKAKSS WFGLRESKEP TQKPSPHPVK PLTAAPVEAS PDRKQPRTSL STALSSGLER LKTVTSGGIQ SVLPASQLGS SVDTKRPKDS AVLDQSAKYY HLTHDELIGL LLQRERELSQ RDEHVQELES YIDRLLVRIM ETSPTLLQIS PGPPK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
基因功能參考文獻：
1. the ability of insulin to increase the appearance of Rip11 at the cell surface involves an inhibition of Rip11 internalisation from the plasma membrane PMID: 26515129
2. The results of this study suggest a requirement for Rab11Fip5, and presumably Rab11, during Hippocampal Long-Term Depression. PMID: 25972173
3. Delivery of Rab11-containing membrane stores effects broad and functional pseudopods during FcgammaR-mediated phagocytosis in mutant cultures of kinesin 5B-expressing cells. PMID: 21149599
4. Rip11 is a Rab11- and AS160-RabGAP-binding protein required for insulin-stimulatd glucose uptake in adipocytes. PMID: 18003705
5. Study shows that both Rab11 and its effector Rip11 participate in insulin granule exocytosis and that Rip11, as a substrate of PKA, regulates the potentiation of exocytosis by cAMP in pancreatic beta-cells. PMID: 19335615
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亞細胞定位：

Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
數據庫鏈接：

KEGG: mmu:52055

STRING: 10090.ENSMUSP00000058305

UniGene: Mm.220334