Recombinant Mouse RING finger protein 165 (Rnf165)

中文名稱：

小鼠Rnf165重組蛋白
貨號：

CSB-YP019851MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Rnf165重組蛋白
貨號：

CSB-EP019851MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Rnf165重組蛋白
貨號：

CSB-EP019851MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rnf165重組蛋白
貨號：

CSB-BP019851MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rnf165重組蛋白
貨號：

CSB-MP019851MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rnf165
Uniprot No.：

E9QAU8
別名：

Rnf165; Ark2c; Gm96; E3 ubiquitin-protein ligase RNF165; EC 2.3.2.27; Arkadia-like protein 2C; Ark2C; RING finger protein 165
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-347
氨基酸序列

MVLVHVGYLV LPVFGSVRNR GAPFQRSQHP HATSCRHFHL GPPQPQQLAP DFPLAHPVQS QPGLSAHMAP AHQHSGTLHQ SLTPLPTLQF QDVTGPSFLP QALHQQYLLQ QQLLEAQHRR LVSHPRRNQD RVSVHPHRLH PSFDFGHQLQ TPQPRYLAEG TDWDLSVDAG LSPAQFQVRP IPQHYQHYLA TPRMHHFPRN SSSTQMVVHE IRNYPYPQLH FLALQGLNPS RHTSAVRESY EELLQLEDRL GNVTRGAVQN TIERFTFPHK YKKRRPQDSK GKKDEGEESD TDEKCTICLS MLEDGEDVRR LPCMHLFHQL CVDQWLAMSK KCPICRVDIE TQLGADS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL.
基因功能參考文獻：
1. Ark2C is expressed in the nervous system in mice, and its loss leads to motor neuron axon extension and muscle innervation deficits. PMID: 23610558
亞細胞定位：

Nucleus.
蛋白家族：

Arkadia family
組織特異性：

Expressed in neurons of the nervous system.
數據庫鏈接：

KEGG: mmu:225743

STRING: 10090.ENSMUSP00000026494

UniGene: Mm.23293