Recombinant Mouse Platelet endothelial aggregation receptor 1 (Pear1), partial

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中文名稱：

小鼠Pear1重組蛋白
品名簡(jiǎn)稱：

Recombinant Mouse Pear1 protein, partial
貨號(hào)：

CSB-EP017765MO4b0
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：

￥1836
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

Pear1
Uniprot No.：

Q8VIK5
別名：

mPEAR1;Jagged and Delta protein;Protein Jedi;Multiple epidermal growth factor-like domains protein 12;Multiple EGF-like domains protein 12
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Partial
來(lái)源：

E.coli
分子量：

34.9 kDa
表達(dá)區(qū)域：

776-1034aa
氨基酸序列

GYRQWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGSQLFVSSQAPERPSRAHGRENHVTLPADWKHRREPHERGASHLDRSYSCSYSHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPSLPGEPRESGYVEMKGPPSVSPPRQSLHLRDRQQRQLQPQRDSGTYEQPSPLSHNEESLGSTPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells.
基因功能參考文獻(xiàn)：
1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis. PMID: 26156496
2. Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch signaling pathway. PMID: 17226770
3. a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein PMID: 19915564
亞細(xì)胞定位：

Cell membrane; Single-pass membrane protein.
蛋白家族：

MEGF family
組織特異性：

Expressed in thymocytes, bone marrow stromal and osteogenic cells (at protein level). Strongly expressed in kidney and heart. Moderately expressed in lung, spleen, thymus, liver, brain, testis, skin and stomach. Expressed in hematopoietic stem progenitor
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:73182

STRING: 10090.ENSMUSP00000029714

UniGene: Mm.158962