Recombinant Mouse Ornithine decarboxylase antizyme 3 (Oaz3)

中文名稱：

小鼠Oaz3重組蛋白
貨號(hào)：

CSB-YP016247MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

小鼠Oaz3重組蛋白
貨號(hào)：

CSB-EP016247MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

小鼠Oaz3重組蛋白
貨號(hào)：

CSB-EP016247MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Oaz3重組蛋白
貨號(hào)：

CSB-BP016247MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

小鼠Oaz3重組蛋白
貨號(hào)：

CSB-MP016247MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Oaz3
Uniprot No.：

Q9R109
別名：

Oaz3; Ornithine decarboxylase antizyme 3; AZ3; ODC-Az 3; OAZ-t
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-195
氨基酸序列

MLPCCYKSIT YKEQEDLTLR PHCCLPCSCL PCSCLQCSES LGGLQVGRST AQEKDHSQLK ELYSAGNLTV LSTDPLLHQD PVQLDFHFRL TPHSSAHWHG LLCDHRLFLD IPYQALDQGN RESLTATLEY VEEKTNVDSV FVNFQIDRKD RGALLRAFSY MGFEVVRPDH PALPPWDNVI FMVYPLERDL GHPGQ
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.
基因功能參考文獻(xiàn)：
1. Results indicated that OAZ-t is essential for the formation of a rigid junction between the head and tail during spermatogenesis. PMID: 19893612
2. results define the transcriptional regulatory elements of the OAZt gene promoter; an initiator, a downstream element, and two cyclic adenosine monophosphate-responsive element (CRE)-like sites in the upstream region PMID: 14960325
3. antizyme expression requires programmed, ribosomal frameshifting PMID: 10781085
亞細(xì)胞定位：

Nucleus. Cytoplasm.
蛋白家族：

ODC antizyme family
組織特異性：

Testis specific. Expressed throughout the differentiation process from spermatids to spermatozoa in the inner part of the seminiferous tubules.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:53814

STRING: 10090.ENSMUSP00000029787

UniGene: Mm.440422