Recombinant Mouse Neutral amino acid transporter A (Slc1a4), partial

中文名稱：

小鼠Slc1a4重組蛋白
貨號：

CSB-YP021435MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Slc1a4重組蛋白
貨號：

CSB-EP021435MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Slc1a4重組蛋白
貨號：

CSB-EP021435MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slc1a4重組蛋白
貨號：

CSB-BP021435MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slc1a4重組蛋白
貨號：

CSB-MP021435MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc1a4
Uniprot No.：

O35874
別名：

Slc1a4; Asct1; Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; SATT; Solute carrier family 1 member 4
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.
基因功能參考文獻(xiàn)：
1. ASCT1, rather than ASCT2, is a component of the brain serine shuttle. ASCT1-KO mice display motor and neurodevelopmental deficits reminiscent of ASCT1 missense mutations in humans. PMID: 30185558
2. used as receptor by HERV-W Env glycoprotein when their sites for N-glycosylation are eliminated by mutagenesis PMID: 12050356
3. ASCT1 expression was gradually downregulated in neuronal populations during late embryonic and neonatal periods, whereas its high expression was transmitted to radial glial cells and then to astrocytes; ASCT1 appears regulated to meet metabolic demands PMID: 12533615
4. either Phgdh or ASCT1 is provided to each segment of renal tubules, suggesting that metabolic interplay mediated by L-serine biosynthesis and supply may exist in the kidney PMID: 17510490
5. Results demonstrate injury-induced changes in Phgdh and ASCT1 expression. PMID: 18751891
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亞細(xì)胞定位：

Membrane; Multi-pass membrane protein. Melanosome.
蛋白家族：

Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family, SLC1A4 subfamily
數(shù)據(jù)庫鏈接：

KEGG: mmu:55963

STRING: 10090.ENSMUSP00000105223

UniGene: Mm.6379