Recombinant Mouse Neurogenic differentiation factor 4 (Neurod4)

中文名稱：

小鼠Neurod4重組蛋白
貨號：

CSB-YP015727MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Neurod4重組蛋白
貨號：

CSB-EP015727MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Neurod4重組蛋白
貨號：

CSB-EP015727MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Neurod4重組蛋白
貨號：

CSB-BP015727MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Neurod4重組蛋白
貨號：

CSB-MP015727MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Neurod4
Uniprot No.：

O09105
別名：

Neurod4; Ath3; Atoh3; Neurogenic differentiation factor 4; NeuroD4; Helix-loop-helix protein mATH-3; mATH3; Protein atonal homolog 3
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-330
氨基酸序列

MAKMYMKSKD MVELVNTQSW MDKGLSSQNE MKEQERRPGS YGMLGTLTEE HDSIEEDEEE EEDGDKPKRR GPKKKKMTKA RLERFRARRV KANARERTRM HGLNDALDNL RRVMPCYSKT QKLSKIETLR LARNYIWALS EVLETGQTLE GKGFVEMLCK GLSQPTSNLV AGCLQLGPQS TLLEKHEEKS SICDSTISVH SFNYQSPGLP SPPYGHMETH SLHLKPQPFK SLGDSFGSHP PDCSTPPYEG PLTPPLSISG NFSLKQDGSP DLEKSYNFMP HYTSASLSSG HVHSTPFQTG TPRYDVPVDL SYDSYSHHSI GTQLNTIFSD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina.
基因功能參考文獻：
1. In the sensory ganglia, early expression of NeuroD4 is terminated in mid gestation by Brn3a and Isl1 which bind to a shared enhancer in the NeuroD4 locus. PMID: 21734270
2. Math3 are essential, but not sufficient, for amacrine cell genesis. PMID: 11861467
3. Mash1 and Math3 promote branchiomotor neuron development and also regulate subsequent oligodendrocyte development and cytoarchitecture by maintaining neural progenitors through Notch signaling. PMID: 15976074
4. Neurod4 cooperates to specify a cortical projection neuron identity. PMID: 18160702
亞細胞定位：

Nucleus.
組織特異性：

Expressed in retinal interneurons amacrine cells (at protein level). Expressed in neurons of ventricular zone of the retina at postnatal day 1 (P1). Expressed transiently in amacrine and horizontal cells of the inner nuclear layer (INL) of the retina at P
數據庫鏈接：

KEGG: mmu:11923

STRING: 10090.ENSMUSP00000051379

UniGene: Mm.10695