Recombinant Mouse NF-kappa-B inhibitor epsilon (Nfkbie)

中文名稱：

小鼠Nfkbie重組蛋白
貨號：

CSB-YP015764MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nfkbie重組蛋白
貨號：

CSB-EP015764MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nfkbie重組蛋白
貨號：

CSB-EP015764MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nfkbie重組蛋白
貨號：

CSB-BP015764MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nfkbie重組蛋白
貨號：

CSB-MP015764MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nfkbie
Uniprot No.：

O54910
別名：

Nfkbie; Ikbe; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilon
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-364
氨基酸序列

MSDARKGPDE ADDSQCDSGI ESLRSLRSLP EPTAAPGSGS SQSGCPQPWR HAPETHKEPE KEDADGERAD STYASSSLTE SFPLLERPEA KDPSPPAPGS PLPPAGVLSP QQLEALTYIS EDGDTLLHLA VIHEAPSVLF CCLAFLPQEV LDIQNNLYQT ALHLAVHLDQ PDVVRALVLK GASRILQDQH GDTALHVACR RQNLACACCL LEEQPEPGRQ LSHPLDLQLK NWQGLACLHI ATLQRNQPLI ELLLQNGADI DVQEGTSGKT ALHLAVETQE RSLVQFLLQA GARVDARMLN GCTPLHLAAG RGLNSISSTL CEAGADSLLL NVEDETPQDL AEDLLSYLPF DDLKISGKPL LCTD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
基因功能參考文獻：
1. The data imply that regulation of these c-Rel-dependent lymphoid responses is a non-redundant function of IkappaBepsilon. PMID: 21915344
2. IkappaBepsilon deficiency in mice leads to neonatal death, elevated kappaB binding activity, overexpression of NF-kappaB target genes, and disruption of lymphocyte production. PMID: 14665694
3. An important role is proposed for I kappa B epsilon in the differential regulation of nuclear NF-kappa B activity in stimulated B cells. PMID: 15634922
亞細胞定位：

Cytoplasm.
蛋白家族：

NF-kappa-B inhibitor family
數據庫鏈接：

KEGG: mmu:18037

STRING: 10090.ENSMUSP00000024742

UniGene: Mm.57043