Recombinant Mouse Lysozyme C-2 (Lyz2)

^{In
Stock}

中文名稱：

小鼠Lyz2重組蛋白
品名簡稱：

Recombinant Mouse Lyz2 protein
貨號：

CSB-EP357518MO
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

Lyz2
Uniprot No.：

P08905
別名：

Lyz2; Lyz; LyzsLysozyme C-2; EC 3.2.1.17; 1,4-beta-N-acetylmuramidase C; Lysozyme C type M
種屬：

Mus musculus(Mouse)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

19.8 kDa
表達區域：

19-148aa
氨基酸序列

KVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCSALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged and C-terminal Myc-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer，50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz2 is active against a range of Gram-positive and Gram-negative bacteria. More effective than Lyz1 in killing Gram-negative bacteria. Lyz1 and Lyz2 are equally effective in killing Gram-positive bacteria.
基因功能參考文獻：
1. Results show that lysozyme (LYSO) - induced Staphylococcus aureus bacteriostasis increased with increasing concentrations of baicalin, and that baicalin binding to LYSO synergistically increased the antibacterial activity of LYSO. PMID: 28184027
2. Data show that receptor-interacting serine-threonine kinase 3 (RIPK3) deletion prevents inflammatory phenotypes in CreLysM (lysozyme M) Casp8fl/fl (caspase 8) mice. PMID: 26471282
3. Depletion of LysM(+) cells attenuated ATII-induced blood pressure increase. PMID: 21875910
4. ApoE and lysozyme M have roles in monocyte and neutrophil trafficking in atherosclerosis in a mouse model PMID: 18508059
5. P-tau was found in medial entorhinal cortex of Naglu(-/-) mice, in the same neurons as lysozyme PMID: 19416848
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亞細胞定位：

Secreted.
蛋白家族：

Glycosyl hydrolase 22 family
組織特異性：

Expressed weakly in myeloblasts, moderately in immature macrophages, and strongly in both mature macrophages and macrophage-rich tissues.
數據庫鏈接：

KEGG: mmu:17105

STRING: 10090.ENSMUSP00000089801

UniGene: Mm.45436