Recombinant Mouse Inositol hexakisphosphate kinase 2 (Ip6k2)

中文名稱：

小鼠Ip6k2重組蛋白
貨號：

CSB-YP011771MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Ip6k2重組蛋白
貨號：

CSB-EP011771MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Ip6k2重組蛋白
貨號：

CSB-EP011771MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ip6k2重組蛋白
貨號：

CSB-BP011771MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ip6k2重組蛋白
貨號：

CSB-MP011771MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ip6k2
Uniprot No.：

Q80V72
別名：

Ip6k2; Ihpk2; Inositol hexakisphosphate kinase 2; InsP6 kinase 2; EC 2.7.4.-; P(i)-uptake stimulator; PiUS
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-448
氨基酸序列

MSPAFRTMDV EPRTKGILLE PFVHQVGGHS CVLRFNETTL CKPLVPREHQ FYETLPAEMR RFTPQYKAVL IFVRCADEFG ASGNIETKEQ GVVSVRFEED EDRNLCLIAY PLKGDHGTVD IVDNSDCEPK SKLLRWTNKK HHALETEKNP KDWVRQHRKE EKMKSHKLEE EFEWLKKSEV LYYSVEKKGN VSSQLKHYNP WSMKCHQQQL QRMKENAKHR NQYKFILLEN LTSRYEVPCV LDLKMGTRQH GDDASEEKAA NQIRKCQQST SAVIGVRVCG MQVYQAGTGQ LMFMNKYHGR KLSVQGFKEA LFQFFHNGRY LRRELLGPVL KKLTELKAVL ERQESYRFYS SSLLVIYDGK EWPEVTLDSD AEDLEDLSEE SADESAGAYA YKPIGASSVD VRMIDFAHTT CRLYGEDSVV HEGQDAGYIF GLQSLIDIVT EISEESGE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). May play a role in the regulation of Na(+)-dependent phosphate cotransport, possibly via its role in diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) biosynthesis.
基因功能參考文獻：
1. IP6K2 is a major mediator of cancer cell migration and tumor metastasis, acting by enhancing cell-matrix adhesion and decreasing cell-cell adhesion. PMID: 25617365
2. FGF2-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 and osteoblast gene expression. PMID: 23322705
3. Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. PMID: 19430495
亞細胞定位：

Nucleus.
蛋白家族：

Inositol phosphokinase (IPK) family
組織特異性：

Highly expressed in brain and lung, and at slightly lower levels in liver, kidney and testis.
數據庫鏈接：

KEGG: mmu:76500

STRING: 10090.ENSMUSP00000082091

UniGene: Mm.276336