Recombinant Mouse Immediate early response gene 2 protein (Ier2)

中文名稱(chēng)：

小鼠Ier2重組蛋白
貨號(hào)：

CSB-YP011001MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

小鼠Ier2重組蛋白
貨號(hào)：

CSB-EP011001MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

小鼠Ier2重組蛋白
貨號(hào)：

CSB-EP011001MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

小鼠Ier2重組蛋白
貨號(hào)：

CSB-BP011001MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

小鼠Ier2重組蛋白
貨號(hào)：

CSB-MP011001MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ier2
Uniprot No.：

P17950
別名：

Ier2; Immediate early response gene 2 protein; CHX1; Cycloheximide-induced gene protein; Growth factor-inducible immediate early protein; Proline-rich-induced protein 92; Pip92; T-lymphocyte-activated protein
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full length protein
表達(dá)區(qū)域：

1-221
氨基酸序列

MEVQKEAQRI MTLSVWKMYH SRMQRGGLRL HRSLQLSLVM RSAREVYLSA KVEAHQPEFP PSRRALDPRL HPPREAEVAV EVASPEAVQP PEPMDTQEEV LRVQETPALC DPPPARVSRK RRSSSDLSDG SDAGLVPSKK ARLEEVEGEA TSEVPDRLQL PPAQSEGAFP NLARVLQRRF SSLLNCGPAV PPPTPPTCEA KPACRPADNM LNVLVRAVVA F
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

DNA-binding protein that seems to act as a transcription factor. Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis.
基因功能參考文獻(xiàn)：
1. Relief of contact inhibition was associated with translocation of the Ier2 protein from the cytoplasm to the nucleus in both 3T3 fibroblasts and 1AS tumor cells PMID: 22120713
2. shows a rapid and long-lasting induction after cerebral ischemia; induces cell death in primary neurons and displays several hallmarks of pro-apoptotic activity upon overexpression PMID: 14747749
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

IER family
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:15936

STRING: 10090.ENSMUSP00000060275

UniGene: Mm.399