Recombinant Mouse Homeobox protein Meis3 (Meis3)

中文名稱：

小鼠Meis3重組蛋白
貨號：

CSB-YP013688MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Meis3重組蛋白
貨號：

CSB-EP013688MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Meis3重組蛋白
貨號：

CSB-EP013688MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Meis3重組蛋白
貨號：

CSB-BP013688MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Meis3重組蛋白
貨號：

CSB-MP013688MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Meis3
Uniprot No.：

P97368
別名：

Meis3; Mrg2; Homeobox protein Meis3; Meis1-related protein 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-378
氨基酸序列

MARRYDELRH YPGITEHTTA LASFSEAAPS VPRAPGPYTP HRPPQLQAPG LDSDSLKREK DDIYGHPLFP LLALVFEKCE LATCSPRDGA SAGLGSPPGG DVCSSDSFNE DIAAFAKQIR SERPLFSSNP ELDNLMVQAI QVLRFHLLEL EKVHDLCDNF CHRYITCLKG KMPIDLVIED RDGSCREDLE DYAASCPSLP DQNTTWIRDH EDSGSVHLGT PGPSSGGLAS QSGDNSSDQG DGLDTSVASP SSAGEDEDLD LERRRNKKRG IFPKVATNIM RAWLFQHLSH PYPSEEQKKQ LAQDTGLTIL QVNNWFINAR RRIVQPMIDQ SNRTGQGASF NPEGQPMAGF TETQPQVTVR TPGSMGMNLN LEGEWHYL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.
基因功能參考文獻：
1. Meis3 is abundantly expressed in pancreatic islets and beta-cells and regulates beta-cell survival through 3-phosphoinositide-dependent protein kinase 1 (PDK1). PMID: 21059917
2. The mRNA level of this protein was elevated in limb buds after treatment with ectopic acid. PMID: 12397630
亞細胞定位：

Nucleus.
蛋白家族：

TALE/MEIS homeobox family
組織特異性：

Expressed at high levels in the brain. Significant expression also observed in the heart, spleen and lung. Expressed in pancreatic islets (beta-cells and non-beta-cells).
數據庫鏈接：

KEGG: mmu:17537

STRING: 10090.ENSMUSP00000002495

UniGene: Mm.360516