Recombinant Mouse Exonuclease 3'-5' domain-containing protein 1 (Exd1)

中文名稱：

小鼠Exd1重組蛋白
貨號：

CSB-YP806048MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Exd1重組蛋白
貨號：

CSB-EP806048MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Exd1重組蛋白
貨號：

CSB-EP806048MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Exd1重組蛋白
貨號：

CSB-BP806048MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Exd1重組蛋白
貨號：

CSB-MP806048MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Exd1
Uniprot No.：

Q8CDF7
別名：

Exd1; Exdl1piRNA biogenesis protein EXD1; Exonuclease 3'-5' domain-containing protein 1; Exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1; mExd1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-570
氨基酸序列

MDPSSDYHFL NQILWRRVKL TLVSGIFEGV LQHVDPNKIV VLKNVRNAES GRSVPGVKVF FGHEILNVEL MDEAEGASGE KASAVSINTE RAGMEKVKNE DVNVCEPASP APEVPTSSLL SDLKYCPSEE EEVTYTVIDQ FQQKFGAAML HIKKQSVLSV AAEGANVCRH GKLCWLQVAT NSRVYLFDIF LLGSRAFNNG LQMILEDKRI LKVIHDCRWL SDCLSHQYGI MLNNVFDTQV ADVLQFSMET GGFLPNCIST LQESLIRHLK VAPRYLFFLE ERQKRIQENP EIWLTRPLPP SLLKILALET TYLLPLRLVL LDEVMSDLTT LVDGYLNTYR EGSADRLAGT EPACMELPAE LLQLQDFQKQ RRERAVKEYR VNARGLLIRT PLHPKEPTAC TAGKEERVQG FLFYKTDGGD QVPRFLCPKS HEDEKFLDKE SKQTTAKSQI VPPRKEGEAH KDSKNKPGCW ESAGPEDPRA QKAHALPPTW ASQSQFSLKE EIEQLTVVGN KGALTSPKEG ALVSPSLLQE TWEAPTDTFH LPEKAEVSTL PPCPALEKTD SWISPSLNLF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease.
基因功能參考文獻：
1. piRNA biogenesis triggered by PIWI slicing, and promoted by EXD1, ensures that the same guides instruct PIWI proteins in the nucleus and cytoplasm. PMID: 26669262
亞細胞定位：

Cytoplasm.
蛋白家族：

EXD1 family
數據庫鏈接：

KEGG: mmu:241624

STRING: 10090.ENSMUSP00000054980

UniGene: Mm.212773