Recombinant Mouse E3 ubiquitin-protein ligase Rnf220 (Rnf220)

中文名稱(chēng)：

小鼠Rnf220重組蛋白
貨號(hào)：

CSB-YP747472MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

小鼠Rnf220重組蛋白
貨號(hào)：

CSB-EP747472MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

小鼠Rnf220重組蛋白
貨號(hào)：

CSB-EP747472MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

小鼠Rnf220重組蛋白
貨號(hào)：

CSB-BP747472MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

小鼠Rnf220重組蛋白
貨號(hào)：

CSB-MP747472MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rnf220
Uniprot No.：

Q6PDX6
別名：

Rnf220; E3 ubiquitin-protein ligase Rnf220; EC 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase Rnf220
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-566
氨基酸序列

MDLHRAAFKM ENSSYLPNPL ASPALMVLAS TAEASRDASI PCQQPRPFGV PVSVDKDVHI PFTNGSYTFA SMYHRQGGVP GTFANRDFPP SLLHLHPQFA PPNLDCTPIS MLNHSGVGAF RPFASTEDRE SYQSAFTPAK RLKNCHDTES PHLRFSDADG KEYDFGTQLP SSSPGSLKVD DTGKKIFAVS GLISDRETSS SPEDRNDRCK KKAVALFDSQ APLCPICQVL LRPSELQEHM EQELEQLAQL PASKNSLLKD AMAPGTPKSL LLSASIKREG DSPTASPHSS ATEDLHHSDR YQTFLRVRAN RQTRLNARIG KMKRRKQDEG QREGSCMAED DAVDIEHADS NRFEEYEWCG QKRIRATTLL EGGFRGSGFV MCSGKENPDS DADLDVDGDD TLEYGKPQYT EADVIPCTGE EPGEAKEREA LRGAVLNGGP PSTRITPEFS KWASDEMPST SNGEGSKQEA MQKTCKNSDI EKITEESAVT TFEALKARVR ELERQLSRGD RYKCLICMDS YSMPLTSIQC WHVHCEECWL RTLGAKKLCP QCNTITAPGD LRRIYL
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 and promotes Wnt signaling.
基因功能參考文獻(xiàn)：
1. RNF220 plays crucial roles in the patterning of the ventral progenitor domains, by targeting multiple transcription factors, including Dbx1/2 and Nkx2.2, for degradation in close cooperation with ZC4H2. PMID: 30177510
亞細(xì)胞定位：

Cytoplasm.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:66743

STRING: 10090.ENSMUSP00000030439

UniGene: Mm.318331