Recombinant Mouse Deoxycytidine kinase (Dck)

中文名稱：

Recombinant Mouse Deoxycytidine kinase(Dck)
貨號：

CSB-YP006547MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Deoxycytidine kinase(Dck)
貨號：

CSB-EP006547MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Deoxycytidine kinase(Dck)
貨號：

CSB-EP006547MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Deoxycytidine kinase(Dck)
貨號：

CSB-BP006547MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Deoxycytidine kinase(Dck)
貨號：

CSB-MP006547MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dck
Uniprot No.：

P43346
別名：

DckDeoxycytidine kinase; dCK; EC 2.7.1.74
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-260
氨基酸序列

MATPPKRFCP SPSTSSEGTR IKKISIEGNI AAGKSTFVNI LKQASEDWEV VPEPVARWCN VQSTQEEFEE LTTSQKSGGN VLQMMYEKPE RWSFTFQSYA CLSRIRAQLA SLNGKLKDAE KPVLFFERSV YSDRYIFASN LYESDCMNET EWTIYQDWHD WMNSQFGQSL ELDGIIYLRA TPEKCLNRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTSFDYLQE VPVLTLDVNE DFKDKHESLV EKVKEFLSTL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine.
基因功能參考文獻：
1. Mutation of a single serine 74 residue has profound effects on murine T and B lymphocyte development, suggesting that post-translational regulation of dCK has a role in maintaining genomic stability during hematopoiesis. PMID: 25101980
2. activating the dAdo-DCK-dATP pathway directly results in increased apoptosis in the lungs of mice with air-space enlargement and suggests a novel therapeutic target for the treatment of COPD PMID: 23392349
3. Deoxycytidine kinase is a new regulator of hematopoietic integrity and lymphocyte quiescence and survival. PMID: 22407915
4. The severe impact of dCK inactivation on lymphopoiesis was unexpected given that nucleoside salvage has been thought to play a limited, "fine-tuning" role in regulating deoxyribonucleotide triphosphate pools produced by the de novo pathway. PMID: 20080663
亞細胞定位：

Nucleus.
蛋白家族：

DCK/DGK family
數據庫鏈接：

KEGG: mmu:13178

STRING: 10090.ENSMUSP00000031311

UniGene: Mm.298892