Recombinant Mouse Carboxylesterase 1C (Ces1c), partial

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中文名稱：

Recombinant Mouse Carboxylesterase 1C(Ces1c),partial
品名簡稱：

Recombinant Mouse Ces1c protein, partial
貨號：

CSB-YP338557MO
說明書：

MSDS Datasheet
規格：

￥2208
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP338557MO could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Ces1c.

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP338557MO could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Ces1c.

The purity of Ces1c was greater than 95% as determined by SEC-HPLC
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
Greater than 95% as determined by SEC-HPLC.
基因名：

Ces1c
Uniprot No.：

P23953
別名：

Carboxylesterase 1C; Ces N; Ces1c; Ee 1; Ee 4; Ee1; Es N; Es1; Es4; EsN; EST1C_MOUSE; Esterase 1; Liver carboxylesterase N; Lung surfactant convertase; PES-N; PESN
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
來源：

Yeast
分子量：

60.6kDa
表達區域：

19-550aa
氨基酸序列

HSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASPYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQYNISLSTMIDGVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPMMLQNLLPEGKMNEETASLLLRRFHSELNISESMIPAVIEQYLRGVDDPAKKSELILDMFGDIFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFFVFGAPLLKEGASEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEQEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產品描述：

小鼠羧酸酯酶1C（Ces1c）是一種重要的絲氨酸水解酶家族成員，主要分布于人體肝臟中，腸道組織中幾乎沒有。在小鼠中，Ces1c的缺失會影響藥物和脂質代謝及穩態。值得注意的是，雖然Ces1c在小鼠中起著重要的作用，但在某些情況下，如藥物開發中，Ces1c的缺失可能會帶來一些問題。例如，Ces1c的缺失可能會導致藥物在小鼠體內的代謝和穩態受到影響。因此，在進行藥物開發時，需要考慮到Ces1c的作用，以便更好地理解和利用其特性。
華美生物的小鼠羧酸酯酶1C（Ces1c）重組蛋白，由酵母表達系統表達，表達區域為1-441aa，具備高純度高穩定性等特點，助您進行相關科學研究。
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
基因功能參考文獻：
1. Phospho-non-steroidal anti-inflammatory drugs hydrolysis in wild-type mouse plasma was 6-530-fold higher than that in the plasma of Ces1c-/- mice. PMID: 25392229
2. Hepatic carboxylesterase 1 is induced by glucose and regulates postprandial glucose levels PMID: 25285996
3. These results identify and characterize ES1 as a novel transcriptional regulator of GHR gene expression. PMID: 21659478
亞細胞定位：

Endoplasmic reticulum lumen. Note=Microsomal membrane, lumen of endoplasmic reticulum.
蛋白家族：

Type-B carboxylesterase/lipase family
組織特異性：

Expressed in lung, kidney and liver.
數據庫鏈接：

KEGG: mmu:13884

STRING: 10090.ENSMUSP00000034189

UniGene: Mm.88078