Recombinant Mouse CAP-Gly domain-containing linker protein 3 (Clip3)

中文名稱：

Recombinant Mouse CAP-Gly domain-containing linker protein 3(Clip3)
貨號：

CSB-YP005555MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse CAP-Gly domain-containing linker protein 3(Clip3)
貨號：

CSB-EP005555MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse CAP-Gly domain-containing linker protein 3(Clip3)
貨號：

CSB-EP005555MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse CAP-Gly domain-containing linker protein 3(Clip3)
貨號：

CSB-BP005555MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse CAP-Gly domain-containing linker protein 3(Clip3)
貨號：

CSB-MP005555MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Clip3
Uniprot No.：

B9EHT4
別名：

Clip3; Clipr59CAP-Gly domain-containing linker protein 3; Cytoplasmic linker protein 170-related 59 kDa protein; CLIP-170-related 59 kDa protein; CLIPR-59
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-547
氨基酸序列

MTKTDPAPMA PPPRGEEEEE EEEDEPVPEA PSPTQERRQK PVVHPSAPAP LPKDYAFTFF DPNDPACQEI LFDPKTTIPE LFAIVRQWVP QVQHKIDVIG NEILRRGCHV NDRDGLTDMT LLHYACKAGA HGVGDPAAAV RLSQQLLALG ADVTLRSRWT NMNALHYAAY FDVPDLVRVL LKGARPRVVN STCSDFNHGS ALHIAASNLC LGAAKCLLEH GANPALRNRK GQVPAEVVPD PMDMSLDKAE AALVAKELRT LLEEAVPLSC TLPKVTLPNY DNVPGNLMLS ALGLRLGDRV LLDGQKTGTL RFCGTTEFAS GQWVGVELDE PEGKNDGSVG GVRYFICPPK QGLFASVSKV SKAVDAPPSS VTSTPRTPRM DFSRVTGKGR REHKGKKKSP SSPSLGSLQQ REGAKAEVGD QVLVAGQKQG IVRFYGKTDF APGYWYGIEL DQPTGKHDGS VFGVRYFTCA PRHGVFAPAS RIQRIGGSTD PPGDSVGAKK VHQVTMTQPK RTFTTVRTPK DIASENSISR LLFCCWFPWM LRAEMQS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes.
基因功能參考文獻：
1. Collectively, our studies demonstrate that formation of an Elmo2.ClipR-59 complex plays an important role in myoblast fusion. PMID: 25572395
2. CLIPR-59 is involved in the stabilization of specific motor axons at the neuromuscular junction during mouse late embryogenesis and its role is crucial for mouse perinatal development. PMID: 23482493
3. Because ClipR-59 also interacts with Akt and enhances the interaction between Akt and AS160, we suggest that ClipR-59 functions as a scaffold protein to facilitate Akt-mediated AS160 phosphorylation, thereby regulating glucose transport PMID: 22689584
4. ClipR-59 functions as a scaffold protein that interacts with phospho-Akt and recruits active Akt on the membrane and may play an important role in adipocyte glucose transport. PMID: 19139280
亞細胞定位：

Cell membrane; Lipid-anchor. Cytoplasm. Golgi apparatus, Golgi stack.
數據庫鏈接：

KEGG: mmu:76686

STRING: 10090.ENSMUSP00000014065

UniGene: Mm.159258