Recombinant Mouse Bone morphogenetic protein 8A (Bmp8a)

中文名稱：

Recombinant Mouse Bone morphogenetic protein 8A(Bmp8a)
貨號：

CSB-YP002745MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Bone morphogenetic protein 8A(Bmp8a)
貨號：

CSB-EP002745MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Bone morphogenetic protein 8A(Bmp8a)
貨號：

CSB-EP002745MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Bone morphogenetic protein 8A(Bmp8a)
貨號：

CSB-BP002745MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Bone morphogenetic protein 8A(Bmp8a)
貨號：

CSB-MP002745MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Bmp8a
Uniprot No.：

P34821
別名：

Bmp8a; Bmp-8; Bmp8Bone morphogenetic protein 8A; BMP-8A; Osteogenic protein 2; OP-2
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

261-399
氨基酸序列

AARPLKRRQP KKTNELPHPN KLPGIFDDGH GSRGREVCRR HELYVSFRDL GWLDWVIAPQ GYSAYYCEGE CAFPLDSCMN ATNHAILQSL VHLMKPDVVP KACCAPTKLS ATSVLYYDSS NNVILRKHRN MVVKACGCH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including spermatogenesis, osteogenesis, steroidogenesis as well as regulation of energy balance. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. In addition, activates the SMAD2/3 pathway.
基因功能參考文獻：
1. Stromal Fgf10 and Bmp8a serve as potential paracrine factors for estrogen-dependent regulation of epithelial proliferation in the uterus. PMID: 25451979
2. BMP-8 might be an essential player in bone metabolism, especially in response to glucocorticoids PMID: 21277400
亞細胞定位：

Secreted.
蛋白家族：

TGF-beta family
組織特異性：

Expressed in testis. expressed in trophoblast cells of the labyrinthine region of the placenta and in the inner root sheath of hair follicles of early postnatal skin. Expressed predominantly in the neonatal mouse spermatogonia.
數據庫鏈接：

KEGG: mmu:12163

STRING: 10090.ENSMUSP00000037779

UniGene: Mm.439749