Recombinant Mouse Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Mthfd2)

中文名稱：

小鼠Mthfd2重組蛋白
貨號：

CSB-YP015156MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mthfd2重組蛋白
貨號：

CSB-EP015156MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mthfd2重組蛋白
貨號：

CSB-EP015156MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mthfd2重組蛋白
貨號：

CSB-BP015156MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mthfd2重組蛋白
貨號：

CSB-MP015156MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mthfd2
Uniprot No.：

P18155
別名：

Mthfd2; Nmdmc; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase; mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase; EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase; EC 3.5.4.9)]
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

36-350
氨基酸序列

EAVVI SGRKLAQQIK QEVQQEVEEW VASGNKRPHL SVILVGDNPA SHSYVLNKTR AAAEVGINSE TIVKPASVSE EELLNSIRKL NNDENVDGLL VQLPLPEHID ERKVCNAVSP DKDVDGFHVI NVGRMCLDQY SMLPATPWGV WEIIKRTGIP TLGKNVVVAG RSKNVGMPIA MLLHTDGAHE RPGGDATVTI SHRYTPKEQL KKHTILADIV ISAAGIPNLI TADMIKEGAA VIDVGINRVQ DPVTAKPKLV GDVDFEGVKK KAGYITPVPG GVGPMTVAML MKNTIIAAKK VLRPEELEVF KSKQRGVATN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
基因功能參考文獻：
1. Mammalian mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase derived from a trifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase. PMID: 12061812
2. results demonstrate a metabolic role for NAD+ dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase in supporting purine biosynthesis PMID: 12646567
3. Results describe the ubiquitous expression of NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase in mouse embryos, suggesting it has a broad role during embryogenesis. PMID: 15342116
4. A mutation in methylenetetrahydrofolate reductase (MTHFR) gene, may contribute to the risk of both arterial and deep-vein thrombosis in patients with nephrotic syndrome. PMID: 18030499
亞細胞定位：

Mitochondrion.
蛋白家族：

Tetrahydrofolate dehydrogenase/cyclohydrolase family
數據庫鏈接：

KEGG: mmu:17768

STRING: 10090.ENSMUSP00000005810

UniGene: Mm.443