Recombinant Mouse BAG family molecular chaperone regulator 5 (Bag5)

中文名稱：

Recombinant Mouse BAG family molecular chaperone regulator 5(Bag5)
貨號：

CSB-YP810608MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse BAG family molecular chaperone regulator 5(Bag5)
貨號：

CSB-EP810608MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse BAG family molecular chaperone regulator 5(Bag5)
貨號：

CSB-EP810608MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse BAG family molecular chaperone regulator 5(Bag5)
貨號：

CSB-BP810608MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse BAG family molecular chaperone regulator 5(Bag5)
貨號：

CSB-MP810608MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Bag5
Uniprot No.：

Q8CI32
別名：

Bag5BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-447
氨基酸序列

MDMGNQHPSI SRLQEIQREV KAIEPQVVGF SGLSDDKNYK RLERILTKQL FEIDSVDTEG KGDIQQARKR AAQETERLLK ELEQNANHPH RIEIQNIFKE AQALVKDKIV PFYSGGNCVT DEFEEGIQDI ILRLTHVKTG GKVSLRKARY RTLTKICAVQ EVIEDCMKKQ PSLPLSEDVH PSVAKINSVM CEVNKARGTL IALLMGVDSS ETCRHLSCVL SGLIADLDAL DVCGRTEIRN YRREVVEDIN KLLKYLDLEE EADSTHAFDL GQNHSIIKIE NVLKRMREIK NELLQAQSPP ELYLRAKTEL QGLIGQLDEV SLEKNPCIRE ARRRAVIEVQ ILITYLDLKE ALEKRKLFPC EEHPPHKAVW EILGNLSEIL GEVLSFGGNR TDKNYIRLEE LLTKQLLALD AVDPQGEEKC KAARKQAVKL AQNILSYLDM KSDEWEY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.
基因功能參考文獻：
1. knockdown of Bag5 exacerbated Abeta1-42-induced apoptosis. PMID: 25367796
2. Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death. PMID: 15603737
數據庫鏈接：

KEGG: mmu:70369

STRING: 10090.ENSMUSP00000051049

UniGene: Mm.44239