Recombinant Mouse Adenylosuccinate synthetase isozyme 1 (Adssl1)

中文名稱：

Recombinant Mouse Adenylosuccinate synthetase isozyme 1(Adssl1)
貨號：

CSB-YP001399MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Adenylosuccinate synthetase isozyme 1(Adssl1)
貨號：

CSB-EP001399MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Adenylosuccinate synthetase isozyme 1(Adssl1)
貨號：

CSB-EP001399MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Adenylosuccinate synthetase isozyme 1(Adssl1)
貨號：

CSB-BP001399MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Adenylosuccinate synthetase isozyme 1(Adssl1)
貨號：

CSB-MP001399MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Adssl1
Uniprot No.：

P28650
別名：

Adss1; Adssl1; Adenylosuccinate synthetase isozyme 1; AMPSase 1; AdSS 1; EC 6.3.4.4; Adenylosuccinate synthetase like 1; Adenylosuccinate synthetase; basic isozyme; Adenylosuccinate synthetase; muscle isozyme; M-type adenylosuccinate synthetase; IMP--aspartate ligase 1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-457
氨基酸序列

MSGTRASNDR PPGTGGVKRG RLQQEAAATG SRVTVVLGAQ WGDEGKGKVV DLLATDADIV SRCQGGNNAG HTVVVDGKEY DFHLLPSGII NTKAVSFIGN GVVIHLPGLF EEAEKNEKKG LKDWEKRLII SDRAHLVFDF HQAVDGLQEV QRQAQEGKNI GTTKKGIGPT YSSKAARTGL RICDLLSDFD EFSARFKNLA HQHQSMFPTL EIDVEGQLKR LKGFAERIRP MVRDGVYFMY EALHGPPKKV LVEGANAALL DIDFGTYPFV TSSNCTVGGV CTGLGIPPQN IGDVYGVVKA YTTRVGIGAF PTEQINEIGD LLQNRGHEWG VTTGRKRRCG WLDLMILRYA HMVNGFTALA LTKLDILDVL SEIKVGISYK LNGKRIPYFP ANQEILQKVE VEYETLPGWK ADTTGARKWE DLPPQAQSYV RFVENHMGVA VKWVGVGKSR ESMIQLF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
基因功能參考文獻：
1. Crystalline complexes presented of the recombinant basic isozyme from mouse PMID: 12004071
2. Adss1 functions as an important component in adenine nucleotide biosynthesis. It is up-regulated in surgically induced cardiomegaly. PMID: 12169208
3. there are antagonistic interactions between the active sites of the basic isozyme of adenylosuccinate synthetase PMID: 12482871
4. The absence of the 2'-hydroxyl group of the deoxyribonucleotide destabilizes binding of the ligand to the L-aspartate pocket of adenylosuccinate synthetase by disrupting hydrogen bonds and by introducing a cavity into the fully ligated active site. PMID: 16981730
5. Deletion of Adenylosuccinate synthetase 1 gene is associated with lung adenocarcinoma. PMID: 19603421
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亞細胞定位：

Cytoplasm. Membrane; Peripheral membrane protein. Note=Partially associated with particulate fractions.
蛋白家族：

Adenylosuccinate synthetase family
組織特異性：

High levels in muscle.
數據庫鏈接：

KEGG: mmu:11565

STRING: 10090.ENSMUSP00000021726

UniGene: Mm.3440