Recombinant Methanococcus vannielii Proteasome-activating nucleotidase (pan)

中文名稱：

Recombinant Methanococcus vannielii Proteasome-activating nucleotidase(pan)
貨號：

CSB-YP409372MNS
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Methanococcus vannielii Proteasome-activating nucleotidase(pan)
貨號：

CSB-EP409372MNS
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Methanococcus vannielii Proteasome-activating nucleotidase(pan)
貨號：

CSB-EP409372MNS-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Methanococcus vannielii Proteasome-activating nucleotidase(pan)
貨號：

CSB-BP409372MNS
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Methanococcus vannielii Proteasome-activating nucleotidase(pan)
貨號：

CSB-MP409372MNS
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

pan
Uniprot No.：

A6UQT3
別名：

pan; Mevan_0952; Proteasome-activating nucleotidase; PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle
種屬：

Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224)
蛋白長度：

full length protein
表達區(qū)域：

1-407
氨基酸序列

MTYPDDYSTD VQKNEMDLKE FKEKAYLAEL ESKVLRLELK NKDITRENVQ IKKENEILKR ELDKLRIPPL ILGTVLDRVN ERKAVVKSST GPNFLVNLSQ FVEPDDIVPG ARVCLNQQTL AVVEVLPKEK DYRAMAMELE EKPDILFGDI GGLNNQIRDI KEVVELPLKN PELFEKVGIV PPKGVLLYGP PGTGKTLLAK AVARETNASF VRVVGSELVK KFIGEGAKLV RDVFKLAKEK SPCIIFIDEI DAVASKRTES LTGGDREVQR TLMQLLAEMD GFDSRGDVKI IAATNRPDIL DPAILRPGRF DRIIEIAAPD EDGRLEIFKI HTDKMNIKSV DLREIAKMAE NMVGADIKAV CTEAGMFAIR EGREYVTTKD FKEALLKVTG KKEKSEEGIA HLTTMYG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
亞細胞定位：

Cytoplasm.
蛋白家族：

AAA ATPase family
數(shù)據(jù)庫鏈接：

KEGG: mvn:Mevan_0952

STRING: 406327.Mevan_0952