Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4 (CSE4)

中文名稱：

Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4(CSE4)
貨號：

CSB-YP721717KBK
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4(CSE4)
貨號：

CSB-EP721717KBK
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4(CSE4)
貨號：

CSB-EP721717KBK-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4(CSE4)
貨號：

CSB-BP721717KBK
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Kluyveromyces lactis Histone H3-like centromeric protein CSE4(CSE4)
貨號：

CSB-MP721717KBK
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CSE4
Uniprot No.：

Q6CTI2
別名：

CSE4; KLLA0C12529g; Histone H3-like centromeric protein CSE4; CENP-A homolog; Chromosome segregation protein 4
種屬：

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
蛋白長度：

full length protein
表達區(qū)域：

1-184
氨基酸序列

MEQSIRSIDG SRSLSNVGAS LIDRESINQR ALQLLQRNRR RRLLLNRSED KARYIQPERS ASSQQIHPPE HHISAHERIT KARGTRYKPT DLALAEIRKY QRSTDLLISR MPFARLVKEV TDQFTTESEP LRWQSMAIMA LQEASEAYLV GLLEHTNLLA LHAKRITIMR KDMQLARRIR GQFI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.
基因功能參考文獻：
1. Data show the structure of a complex formed by an N-terminal fragment of Scm3 (KLLA0F05115g is S. cerevisiae YDL139C SCM3 homolog) with the histone-fold domains of H4 and Cse4 (KLLA0C12529g is S. cerevisiae YKL049C CSE4 homolog). PMID: 21606327
亞細胞定位：

Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.
蛋白家族：

Histone H3 family
數(shù)據(jù)庫鏈接：

KEGG: kla:KLLA0C12529g

STRING: 284590.XP_452757.1