Recombinant Human tRNA (adenine (58)-N (1))-methyltransferase catalytic subunit TRMT61A (TRMT61A)

中文名稱：

人TRMT61A重組蛋白
貨號(hào)：

CSB-YP836214HU
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人TRMT61A重組蛋白
貨號(hào)：

CSB-EP836214HU-B
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TRMT61A重組蛋白
貨號(hào)：

CSB-BP836214HU
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人TRMT61A重組蛋白
貨號(hào)：

CSB-MP836214HU
說(shuō)明書：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

TRMT61A
Uniprot No.：

Q96FX7
別名：

TRMT61A; C14orf172; TRM61; tRNA; adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; EC 2.1.1.220; mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A; EC 2.1.1.-; tRNA(m1A58)-methyltransferase subunit TRMT61A; tRNA(m1A58)MTase subunit TRMT61A
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-289
氨基酸序列

MSFVAYEELI KEGDTAILSL GHGAMVAVRV QRGAQTQTRH GVLRHSVDLI GRPFGSKVTC GRGGWVYVLH PTPELWTLNL PHRTQILYST DIALITMMLE LRPGSVVCES GTGSGSVSHA IIRTIAPTGH LHTVEFHQQR AEKAREEFQE HRVGRWVTVR TQDVCRSGFG VSHVADAVFL DIPSPWEAVG HAWDALKVEG GRFCSFSPCI EQVQRTCQAL AARGFSELST LEVLPQVYNV RTVSLPPPDL GTGTDGPAGS DTSPFRSGTP MKEAVGHTGY LTFATKTPG
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
基因功能參考文獻(xiàn)：
1. we suggest that PKCA tightly controls TRM6/61 activity to prevent translation deregulation that would favor neoplastic development. PMID: 26234676
2. The TRM61 heterotetramer is the only active species, both subunits are required for orientating tRNA for catalysis at Trm61. PMID: 26470919
亞細(xì)胞定位：

Nucleus.
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, TRM61 family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 23790

KEGG: hsa:115708

STRING: 9606.ENSP00000374399

UniGene: Hs.525610