Recombinant Human Zinc transporter 7 (SLC30A7), partial

中文名稱：

人SLC30A7重組蛋白
貨號(hào)：

CSB-YP836732HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人SLC30A7重組蛋白
貨號(hào)：

CSB-EP836732HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人SLC30A7重組蛋白
貨號(hào)：

CSB-EP836732HU1-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SLC30A7重組蛋白
貨號(hào)：

CSB-BP836732HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人SLC30A7重組蛋白
貨號(hào)：

CSB-MP836732HU1
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

SLC30A7
Uniprot No.：

Q8NEW0
別名：

SLC30A7; ZNT7; ZNTL2; Zinc transporter 7; ZnT-7; Solute carrier family 30 member 7; Znt-like transporter 2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
基因功能參考文獻(xiàn)：
1. We observed Bonferroni-corrected statistically significant interactions between albuminuria, urine cadmium levels and polymorphisms in gene SLC30A7 and RAC1. PMID: 28558300
2. Overexpression of ZnT7 is accompanied by activation of PI3K/Akt pathway and inhibiting HG-induced apoptosis. PMID: 23275032
3. Intracellular transporters such as ZnT7, influence the transcellular movement of zinc across the enterocyte PMID: 21462106
4. hZnT-7 is up-regulated in response to cellular zinc depletion in Raji & THP-1 cells. PMID: 17971500
5. Data show that ZNT7 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746
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亞細(xì)胞定位：

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
蛋白家族：

Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
數(shù)據(jù)庫鏈接：

HGNC: 19306

OMIM: 611149

KEGG: hsa:148867

STRING: 9606.ENSP00000350278

UniGene: Hs.533903