Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog (COQ7), partial

中文名稱：

Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog(COQ7), partial
貨號：

CSB-YP859111HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog(COQ7), partial
貨號：

CSB-EP859111HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog(COQ7), partial
貨號：

CSB-EP859111HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog(COQ7), partial
貨號：

CSB-BP859111HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog(COQ7), partial
貨號：

CSB-MP859111HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

COQ7
Uniprot No.：

Q99807
別名：

COQ7; 5-demethoxyubiquinone hydroxylase; mitochondrial; DMQ hydroxylase; EC 1.14.13.-; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7
種屬：

Homo sapiens (Human)
蛋白長度：

partial
表達區域：

37-217
氨基酸序列

SGMT LDNISRAAVD RIIRVDHAGE YGANRIYAGQ MAVLGRTSVG PVIQKMWDQE KDHLKKFNEL MVTFRVRPTV LMPLWNVLGF ALGAGTALLG KEGAMACTVA VEESIAHHYN NQIRTLMEED PEKYEELLQL IKKFRDEELE HHDIGLDHDA ELAPAYAVLK SIIQAGCRVA IYLSERL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
基因功能參考文獻：
1. cCOQ7 COQ7 vCOQ7 PMID: 28409910
2. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. PMID: 25339443
3. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1. PMID: 18927074
4. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1) mRNA levels and activity PMID: 19135146
相關疾病：

Coenzyme Q10 deficiency, primary, 8 (COQ10D8)
亞細胞定位：

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
蛋白家族：

COQ7 family
組織特異性：

Expressed dominantly in heart and skeletal muscle.
數據庫鏈接：

HGNC: 2244

OMIM: 601683

KEGG: hsa:10229

STRING: 9606.ENSP00000322316

UniGene: Hs.157113