Recombinant Human Transcription factor HES-3 (HES3)

中文名稱：

人HES3重組蛋白
貨號：

CSB-YP722582HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人HES3重組蛋白
貨號：

CSB-EP722582HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人HES3重組蛋白
貨號：

CSB-EP722582HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人HES3重組蛋白
貨號：

CSB-BP722582HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人HES3重組蛋白
貨號：

CSB-MP722582HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HES3
Uniprot No.：

Q5TGS1
別名：

HES3; BHLHB43Transcription factor HES-3; Class B basic helix-loop-helix protein 43; bHLHb43; Hairy and enhancer of split 3
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-186
氨基酸序列

MEKKRRARIN VSLEQLKSLL EKHYSHQIRK RKLEKADILE LSVKYMRSLQ NSLQGLWPVP RGAEQPSGFR SCLPGVSQLL RRGDEVGSGL RCPLVPESAA GSTMDSAGLG QEAPALFRPC TPAVWAPAPA AGGPRSPPPL LLLPESLPGS SASVPPPQPA SSRCAESPGL GLRVWRPWGS PGDDLN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional repressor of genes that require a bHLH protein for their transcription.
基因功能參考文獻：
1. The STAT3-Ser/Hes3 Signaling Axis was first identified as a major regulator of neural stem cells and, subsequently, cancer stem cells PMID: 26783739
2. Data show that transcription factor Hes3 is expressed in adult pancreatic islets and dissociated cultures of pancreatic islet cells. PMID: 25371201
3. expression of the transcription factor Hes3 in the mouse and human ocular surface, and in pterygium PMID: 24512568
4. Hes3 is expressed in cultures from glioblastoma multiforme which express neural stem cell markers PMID: 23393614
5. CXorf6 transactivates the Hes3 promoter, augments testosterone production PMID: 18162467
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亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 26226

OMIM: 609971

KEGG: hsa:390992

STRING: 9606.ENSP00000367130

UniGene: Hs.532677