Recombinant Human Teneurin-4 (TENM4), partial

中文名稱：

人TENM4重組蛋白
貨號：

CSB-YP757398HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人TENM4重組蛋白
貨號：

CSB-EP757398HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人TENM4重組蛋白
貨號：

CSB-EP757398HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TENM4重組蛋白
貨號：

CSB-BP757398HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人TENM4重組蛋白
貨號：

CSB-MP757398HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

TENM4
Uniprot No.：

Q6N022
別名：

Protein Odd Oz/ten-m homolog 4; Ten-4; Ten-m4; TEN4_HUMAN; Tenascin-M4; Teneurin transmembrane protein 4; Teneurin-4; tenm4
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer.
基因功能參考文獻(xiàn)：
1. This study demonstrated the TENM4 mutation associate with Essential tremor in Chinese. PMID: 27569844
2. TENM4 is not a cause for essential tremor in a Canadian population. PMID: 28158909
3. Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor. Mutant proteins mislocalize in oligodendrocyte precursor cells. PMID: 26188006
4. the ODZ4 risk variant influences reward processing in the amygdala PMID: 23611537
5. Ten-4 suppresses chondrogenic differentiation and regulates the expression and activation of the key molecules for chondrogenesis PMID: 24648313
6. Data indicate that expression of several predicted chimeric genes and genes with disrupted exon structure including ALK, NBAS, FHIT, PTPRD and ODZ4 in neuroblastoma. PMID: 23991058
7. An intronic variant in ODZ4 is being associated with bipolar disorder. PMID: 21926972
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相關(guān)疾病：

Tremor, hereditary essential 5 (ETM5)
亞細(xì)胞定位：

Cell membrane; Single-pass membrane protein. Cell projection. Nucleus. Cytoplasm.
蛋白家族：

Tenascin family, Teneurin subfamily
數(shù)據(jù)庫鏈接：

HGNC: 29945

OMIM: 610084

KEGG: hsa:26011

STRING: 9606.ENSP00000278550

UniGene: Hs.213087