Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (ANKRD28), partial

中文名稱：

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A(ANKRD28) ,partial
貨號：

CSB-YP001766HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A(ANKRD28) ,partial
貨號：

CSB-EP001766HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A(ANKRD28) ,partial
貨號：

CSB-EP001766HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A(ANKRD28) ,partial
貨號：

CSB-BP001766HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A(ANKRD28) ,partial
貨號：

CSB-MP001766HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
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靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ANKRD28
Uniprot No.：

O15084
別名：

ANKRD28; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; PP6-ARS-A; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A; Ankyrin repeat domain-containing protein 28; Phosphatase interactor targeting protein hnRNP K; PITK
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.
基因功能參考文獻：
1. findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28. PMID: 27026398
2. hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation PMID: 25902538
3. These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity. PMID: 16564677
4. CaMKII and GSK3 mediate regulation of PITK. PMID: 17023142
5. ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. PMID: 19118547
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亞細胞定位：

Nucleus, nucleoplasm. Note=Seems to be excluded from nucleoli.
數(shù)據(jù)庫鏈接：

HGNC: 29024

OMIM: 611122

KEGG: hsa:23243

STRING: 9606.ENSP00000382379

UniGene: Hs.335239