Recombinant Human SPATS2-like protein (SPATS2L)

中文名稱：

人SPATS2L重組蛋白
貨號：

CSB-YP868324HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人SPATS2L重組蛋白
貨號：

CSB-EP868324HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人SPATS2L重組蛋白
貨號：

CSB-EP868324HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SPATS2L重組蛋白
貨號：

CSB-BP868324HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人SPATS2L重組蛋白
貨號：

CSB-MP868324HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SPATS2L
Uniprot No.：

Q9NUQ6
別名：

DNA polymerase-transactivated protein 6; DNAPTP6; SGNP; SPATS2-like protein; Spats2l; Spermatogenesis associated; serine-rich 2-like; SPS2L_HUMAN; Stress granule and nucleolar protein
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-558
氨基酸序列

AELNTHVNV KEKIYAVRSV VPNKSNNEIV LVLQQFDFNV DKAVQAFVDG SAIQVLKEWN MTGKKKNNKR KRSKSKQHQG NKDAKDKVER PEAGPLQPQP PQIQNGPMNG CEKDSSSTDS ANEKPALIPR EKKISILEEP SKALRGVTEG NRLLQQKLSL DGNPKPIHGT TERSDGLQWS AEQPCNPSKP KAKTSPVKSN TPAAHLEIKP DELAKKRGPN IEKSVKDLQR CTVSLTRYRV MIKEEVDSSV KKIKAAFAEL HNCIIDKEVS LMAEMDKVKE EAMEILTARQ KKAEELKRLT DLASQMAEMQ LAELRAEIKH FVSERKYDEE LGKAARFSCD IEQLKAQIML CGEITHPKNN YSSRTPCSSL LPLLNAHAAT SGKQSNFSRK SSTHNKPSEG KAANPKMVSS LPSTADPSHQ TMPANKQNGS SNQRRRFNPQ YHNNRLNGPA KSQGSGNEAE PLGKGNSRHE HRRQPHNGFR PKNKGGAKNQ EASLGMKTPE APAHSEKPRR RQHAADTSEA RPFRGSVGRV SQCNLCPTRI EVSTDAAVLS VPAVTLVA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Down-regulation of SPATS2L expression may be related to the etiology of poor sleep quality and chronic abdominal pain. PMID: 25358868
2. A haplotype of 23 SNPs spanning 131.6 Kb shared by all affected members of 3 linked families with restless legs syndrome was identified. The shared candidate region covers 46.9 Kb over the potassium channel-related gene KCTD18 and exons 10-13 of SPATS2L. PMID: 23054586
3. Our results suggest that SPATS2L may be an important regulator of beta(2)-adrenergic receptor down-regulation and that there is promise in gaining a better understanding of the biological mechanisms of differential response to beta(2)-agonists through GWAS. PMID: 22792082
4. SGNP is localized in both the cytoplasm and nucleolus and defines a non-nucleolar compartment containing 5.8S rRNA. Under oxidative stress, SGNP nucleolar localization decreases and it rapidly co-localizes with stress granules. PMID: 19005571
亞細胞定位：

Cytoplasm. Nucleus, nucleolus. Note=During oxidative stress as well as UV irradiation, energy deprivation or heat shock, relocalizes to cytoplasmic stress granules. In the nucleus, found in structures lacking NPM1.
蛋白家族：

SPATS2 family
數據庫鏈接：

HGNC: 24574

OMIM: 613817

KEGG: hsa:26010

STRING: 9606.ENSP00000351503

UniGene: Hs.120323