Recombinant Human Regulator of G-protein signaling 11 (RGS11)

中文名稱：

人RGS11重組蛋白
貨號：

CSB-YP019643HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人RGS11重組蛋白
貨號：

CSB-EP019643HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人RGS11重組蛋白
貨號：

CSB-EP019643HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RGS11重組蛋白
貨號：

CSB-BP019643HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人RGS11重組蛋白
貨號：

CSB-MP019643HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RGS11
Uniprot No.：

O94810
別名：

Regulator of G protein signaling 11 ; Regulator of G protein signalling 11 ; Regulator of G-protein signaling 11; RGS 11; RGS11; RGS11_HUMAN; RS 11; RS11
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-467
氨基酸序列

MAAGPAPPPG RPRAQMPHLR KMERVVVSMQ DPDQGVKMRS QRLLVTVIPH AVTGSDVVQW LAQKFCVSEE EALHLGAVLV QHGYIYPLRD PRSLMLRPDE TPYRFQTPYF WTSTLRPAAE LDYAIYLAKK NIRKRGTLVD YEKDCYDRLH KKINHAWDLV LMQAREQLRA AKQRSKGDRL VIACQEQTYW LVNRPPPGAP DVLEQGPGRG SCAASRVLMT KSADFHKREI EYFRKALGRT RVKSSVCLEA YLSFCGQRGP HDPLVSGCLP SNPWISDNDA YWVMNAPTVA APTKLRVERW GFSFRELLED PVGRAHFMDF LGKEFSGENL SFWEACEELR YGAQAQVPTL VDAVYEQFLA PGAAHWVNID SRTMEQTLEG LRQPHRYVLD DAQLHIYMLM KKDSYPRFLK SDMYKALLAE AGIPLEMKRR VFPFTWRPRH SSPSPALLPT PVEPTAACGP GGGDGVA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
基因功能參考文獻：
1. Overexpression of RGS11 promotes cell migration, participates in tumor metastasis, and correlates the clinicopathological conditions of patients with lung adenocarcinoma. PMID: 27105500
2. In granulosa cells, there are significant changes in expression during follicular maturation. PMID: 24828608
3. the successful purification of functionally intact Gbeta5-free recombinant RGS11 was reported that differentially interact with R7BP and Galpha(oa). PMID: 19497306
數據庫鏈接：

HGNC: 9993

OMIM: 603895

KEGG: hsa:8786

STRING: 9606.ENSP00000380876

UniGene: Hs.65756