Recombinant Human RNA-binding protein Raly (RALY)

中文名稱：

人RALY重組蛋白
貨號：

CSB-YP892332HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人RALY重組蛋白
貨號：

CSB-EP892332HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人RALY重組蛋白
貨號：

CSB-EP892332HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RALY重組蛋白
貨號：

CSB-BP892332HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人RALY重組蛋白
貨號：

CSB-MP892332HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RALY
Uniprot No.：

Q9UKM9
別名：

Autoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP associated with lethal yellow protein homolog; hnRNP core protein C-like 2; MGC117312; P542; RALY; RALY_HUMAN; RNA binding protein (autoantigenic hnRNP associated with lethal yellow); RNA binding protein (autoantigenic); RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)); RNA-binding protein Raly
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-306
氨基酸序列

SLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG CSVHKGYAFV QYSNERHARA AVLGENGRVL AGQTLDINMA GEPKPDRPKG LKRAASAIYS GYIFDYDYYR DDFYDRLFDY RGRLSPVPVP RAVPVKRPRV TVPLVRRVKT NVPVKLFARS TAVTTSSAKI KLKSSELQAI KTELTQIKSN IDALLSRLEQ IAAEQKANPD GKKKGDGGGA GGGGGGGGSG GGGSGGGGGG GSSRPPAPQE NTTSEAGLPQ GEARTRDDGD EEGLLTHSEE ELEHSQDTDA DDGALQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
基因功能參考文獻：
1. hnRNP RALY regulates PMID: 28972179
2. RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells PMID: 28733251
3. RALY is a poly-U binding protein and as a regulator of H1FX and ANXA1 in mammalian cells. PMID: 28379492
4. People with lower level of RALYL expression had a poorer survival rate. PMID: 22994768
亞細胞定位：

Nucleus.
蛋白家族：

RRM HNRPC family, RALY subfamily
組織特異性：

Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
數據庫鏈接：

HGNC: 15921

OMIM: 614663

KEGG: hsa:22913

STRING: 9606.ENSP00000246194

UniGene: Hs.136947