Recombinant Human Protein transport protein Sec24D (SEC24D), partial

中文名稱：

人SEC24D重組蛋白
貨號：

CSB-YP020953HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人SEC24D重組蛋白
貨號：

CSB-EP020953HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人SEC24D重組蛋白
貨號：

CSB-EP020953HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SEC24D重組蛋白
貨號：

CSB-BP020953HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人SEC24D重組蛋白
貨號：

CSB-MP020953HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SEC24D
Uniprot No.：

O94855
別名：

KIAA0755; Protein transport protein Sec24D; SC24D_HUMAN; SEC24 family member D; SEC24 related gene family; member D; SEC24-related protein D; SEC24D
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5.
基因功能參考文獻：
1. The study found missense mutations in the SEC24D gene in Chinese families with autosomal recessive osteogenesis imperfect. PMID: 27942778
2. three mutant SEC24D alleles in a rare autosomal-recessively inherited skeletal disorder characterized by pre- and postnatal bone fragility, skull ossification defects, craniofacial dysmorphism, and short stature PMID: 25683121
3. Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter PMID: 20889976
4. concentrative endoplasmic reticulum-export is contingent on a direct interaction of GAT1 with Sec24D. PMID: 17210573
相關疾病：

Cole-Carpenter syndrome 2 (CLCRP2)
亞細胞定位：

Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
蛋白家族：

SEC23/SEC24 family, SEC24 subfamily
組織特異性：

Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver.
數據庫鏈接：

HGNC: 10706

OMIM: 607186

KEGG: hsa:9871

STRING: 9606.ENSP00000280551

UniGene: Hs.189641