Recombinant Human Probable ATP-dependent RNA helicase DDX59 (DDX59)

中文名稱：

Recombinant Human Probable ATP-dependent RNA helicase DDX59(DDX59)
貨號：

CSB-YP722563HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Probable ATP-dependent RNA helicase DDX59(DDX59)
貨號：

CSB-EP722563HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Probable ATP-dependent RNA helicase DDX59(DDX59)
貨號：

CSB-EP722563HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Probable ATP-dependent RNA helicase DDX59(DDX59)
貨號：

CSB-BP722563HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Probable ATP-dependent RNA helicase DDX59(DDX59)
貨號：

CSB-MP722563HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

DDX59
Uniprot No.：

Q5T1V6
別名：

DDX 59; DDX59; DDX59_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 ; DEAD box protein 59; DKFZP564B1023; OTTHUMP00000033840; OTTHUMP00000033841; Probable ATP-dependent RNA helicase DDX59; RP11-92G12.2; Zinc finger HIT domain containing protein 5 ; Zinc finger HIT domain-containing protein 5; ZNHIT5
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-619
氨基酸序列

MFVPRSLKIK RNANDDGKSC VAKIIKPDPE DLQLDKSRDV PVDAVATEAA TIDRHISESC PFPSPGGQLA EVHSVSPEQG AKDSHPSEEP VKSFSKTQRW AEPGEPICVV CGRYGEYICD KTDEDVCSLE CKAKHLLQVK EKEEKSKLSN PQKADSEPES PLNASYVYKE HPFILNLQED QIENLKQQLG ILVQGQEVTR PIIDFEHCSL PEVLNHNLKK SGYEVPTPIQ MQMIPVGLLG RDILASADTG SGKTAAFLLP VIMRALFESK TPSALILTPT RELAIQIERQ AKELMSGLPR MKTVLLVGGL PLPPQLYRLQ QHVKVIIATP GRLLDIIKQS SVELCGVKIV VVDEADTMLK MGFQQQVLDI LENIPNDCQT ILVSATIPTS IEQLASQLLH NPVRIITGEK NLPCANVRQI ILWVEDPAKK KKLFEILNDK KLFKPPVLVF VDCKLGADLL SEAVQKITGL KSISIHSEKS QIERKNILKG LLEGDYEVVV STGVLGRGLD LISVRLVVNF DMPSSMDEYV HQIGRVGRLG QNGTAITFIN NNSKRLFWDI AKRVKPTGSI LPPQLLNSPY LHDQKRKEQQ KDKQTQNDLV TGANLMDIIR KHDKSNSQK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Study presents evidence that DDX59 protein can be upregulated by MEK/ERK/MAP kinase pathway downstream of EGFR and Ras signaling. Increased expression of DDX59 mediates the tumorigenecity of EGFR and Ras in lung cancer. PMID: 29133145
2. The novel DDX59 mutation is associated with oral-facial-digital syndrome. PMID: 28711741
3. These data strongly implicate DDX59 RNA helicase family member in the pathogenesis of orofaciodigital syndrome. PMID: 23972372
相關疾病：

Orofaciodigital syndrome 5 (OFD5)
亞細胞定位：

Cytoplasm. Nucleus. Note=Exhibits granular localization in the nucleus, as well as in the cytoplasm.
蛋白家族：

DEAD box helicase family, DDX59 subfamily
組織特異性：

Expressed in fibroblasts (at protein level).
數據庫鏈接：

HGNC: 25360

OMIM: 174300

KEGG: hsa:83479

STRING: 9606.ENSP00000330460

UniGene: Hs.497332