Recombinant Human Probable ATP-dependent DNA helicase HFM1 (HFM1), partial

中文名稱：

人HFM1重組蛋白
貨號：

CSB-YP010325HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人HFM1重組蛋白
貨號：

CSB-EP010325HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人HFM1重組蛋白
貨號：

CSB-EP010325HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人HFM1重組蛋白
貨號：

CSB-BP010325HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人HFM1重組蛋白
貨號：

CSB-MP010325HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HFM1
Uniprot No.：

A2PYH4
別名：

HFM1; SEC3D1Probable ATP-dependent DNA helicase HFM1; EC 3.6.4.12; SEC63 domain-containing protein 1
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
基因功能參考文獻：
1. Data suggest that HFM1 gene might be associated with primary ovarian insufficiency in Chinese population. PMID: 26679638
2. Exome sequencing of two Chinese sisters with primary ovarian insufficiency and their parents identified a shared compound heterozygous mutation in a meiotic gene, HFM1, which encodes a protein necessary for homologous recombination of chromosomes. PMID: 24597873
3. hHFM1 is the evolutionally conserved putative human DNA helicase, which may function as a modulator for genome integrity in germ-line tissues. PMID: 17286053
相關疾病：

Premature ovarian failure 9 (POF9)
蛋白家族：

Helicase family, SKI2 subfamily
組織特異性：

Preferentially expressed in testis and ovary.
數據庫鏈接：

HGNC: 20193

OMIM: 615684

KEGG: hsa:164045

STRING: 9606.ENSP00000359454

UniGene: Hs.454818