Recombinant Human Potassium-transporting ATPase subunit beta (ATP4B), partial
-
中文名稱：Recombinant Human Potassium-transporting ATPase subunit beta (ATP4B), partial
-
品名簡稱：Recombinant Human ATP4B protein, partial
-
貨號(hào)：CSB-MP002343HU
-
說明書：
-
規(guī)格：￥1140
-
圖片：
-
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
-
-
其他：
產(chǎn)品詳情
-
純度：Greater than 95% as determined by SDS-PAGE.
-
生物活性：Not Test
-
基因名：
-
Uniprot No.：
-
種屬：Homo sapiens (Human)
-
蛋白長度：Partial
-
來源：Mammalian cell
-
分子量：30.2 kDa
-
表達(dá)區(qū)域：58-291aa
-
氨基酸序列CLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標(biāo)簽：N-terminal 10xHis-tagged
-
產(chǎn)品提供形式：Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液：If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
-
復(fù)溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
-
儲(chǔ)存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
注意事項(xiàng)：Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
-
Datasheet & COA：Please contact us to get it.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump. Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle.
-
基因功能參考文獻(xiàn)：
- these findings demonstrated that a decrease in pHi, caused by H+/K+-ATPase inhibition induced by BMT-1, triggered the dysfunction of the mitochondria resulting in the apoptosis of MM cells PMID: 24700195
- Downregulation of ATP4B gene is associated with gastric cancer. PMID: 23317218
- BCL-2 inhibits formation of reactive oxygen species. PMID: 11865975
- Content of the beta1 subunit of sodium potassium pump in resistance trained control subjects was 33% higher in trained compared to untrained leg, and 47% higher in trained compared to untrained leg in diabetics. PMID: 14685860
- Thus prolonged exhaustive exercise impaired each of the maximal in vitro Na+-K+-ATPase activity, Ca2+ release, and Ca2+ uptake rates. PMID: 15155714
- Use of fold recognition methods enables the prediction that a C-terminal domain of the beta subunits of Na,K-ATPase and H,K-ATPase has an immunoglobulin-like fold, which resembles cell adhesion molecules. PMID: 19694409
顯示更多
收起更多
-
亞細(xì)胞定位：Apical cell membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
-
蛋白家族：X(+)/potassium ATPases subunit beta family
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
Recombinant Human T-cell immunoreceptor with Ig and ITIM domains (TIGIT), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Mouse Semaphorin-4D (Sema4d), partial (Active)
Express system: Mammalian cell
Species: Mus musculus (Mouse)
-
Recombinant Human Heat-stable enterotoxin receptor (GUCY2C), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human IGF-like family receptor 1 (IGFLR1), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Signal transducer CD24 (CD24)-Nanoparticle (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Rabbit Tissue factor pathway inhibitor (TFPI) (Active)
Express system: Mammalian cell
Species: Oryctolagus cuniculus (Rabbit)
-
-AC1.jpg)
Recombinant Human C-X-C chemokine receptor type 4 (CXCR4)-VLPs (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
