Recombinant Human Peptidyl-prolyl cis-trans isomerase C (PPIC)

中文名稱：

人PPIC重組蛋白
貨號：

CSB-YP018473HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人PPIC重組蛋白
貨號：

CSB-EP018473HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人PPIC重組蛋白
貨號：

CSB-EP018473HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PPIC重組蛋白
貨號：

CSB-BP018473HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人PPIC重組蛋白
貨號：

CSB-MP018473HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PPIC
Uniprot No.：

P45877
別名：

Cyclophilin C; CYPC; MGC3673; Parvulin; Peptidyl prolyl cis trans isomerase C; Peptidyl-prolyl cis-trans isomerase C; Peptidylprolyl isomerase C (cyclophilin C); peptidylprolyl isomerase C; PPIase C; ppiC; PPIC_HUMAN; Rotamase C
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-212
氨基酸序列

MGPGPRLLLP LVLCVGLGAL VFSSGAEGFR KRGPSVTAKV FFDVRIGDKD VGRIVIGLFG KVVPKTVENF VALATGEKGY GYKGSKFHRV IKDFMIQGGD ITTGDGTGGV SIYGETFPDE NFKLKHYGIG WVSMANAGPD TNGSQFFITL TKPTWLDGKH VVFGKVIDGM TVVHSIELQA TDGHDRPLTN CSIINSGKID VKTPFVVEIA DW
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
基因功能參考文獻：
1. Independent validation with glioma patients tissue (n = 70) and normal brain tissue (n = 19) found PPIC, EMP3 and CHI3L1 were up-regulated in glioma tissue. Survival value validation showed that the three genes correlated with patient survival by Kaplan-Meir analysis, including grades, age and therapy. PMID: 27801851
2. Cyclophilin C participates in cytomegalovirus US2 protein-mediated degradation of major histocompatibility complex class I molecules. PMID: 26691022
亞細胞定位：

Cytoplasm.
蛋白家族：

Cyclophilin-type PPIase family
組織特異性：

Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain.
數據庫鏈接：

HGNC: 9256

OMIM: 123842

KEGG: hsa:5480

STRING: 9606.ENSP00000303057

UniGene: Hs.110364