Recombinant Human Methionine--tRNA ligase, mitochondrial (MARS2)

中文名稱：

人MARS2重組蛋白
貨號：

CSB-YP836221HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人MARS2重組蛋白
貨號：

CSB-EP836221HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人MARS2重組蛋白
貨號：

CSB-EP836221HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MARS2重組蛋白
貨號：

CSB-BP836221HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人MARS2重組蛋白
貨號：

CSB-MP836221HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MARS2
Uniprot No.：

Q96GW9
別名：

mars2; Methionine tRNA ligase 2; Methionine tRNA ligase 2 mitochondrial; Methionine tRNA ligase; Methionine tRNA synthetase 2; Methionine--tRNA ligase; Methionyl tRNA synthetase 2 mitochondrial; Methionyl tRNA synthetase mitochondrial; Methionyl-tRNA synthetase 2; MetRS ; mitochondrial; Mitochondrial methionine tRNA ligase; Mitochondrial methionyl tRNA synthetase; Mitochondrial methionyl-tRNA synthetase; MtMetRS; SYMM_HUMAN
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

30-593
氨基酸序列

S SGSLSAGDDA CDVRAYFTTP IFYVNAAPHI GHLYSALLAD ALCRHRRLRG PSTAATRFST GTDEHGLKIQ QAAATAGLAP TELCDRVSEQ FQQLFQEAGI SCTDFIRTTE ARHRVAVQHF WGVLKSRGLL YKGVYEGWYC ASDECFLPEA KVTQQPGPSG DSFPVSLESG HPVSWTKEEN YIFRLSQFRK PLQRWLRGNP QAITPEPFHH VVLQWLDEEL PDLSVSRRSS HLHWGIPVPG DDSQTIYVWL DALVNYLTVI GYPNAEFKSW WPATSHIIGK DILKFHAIYW PAFLLGAGMS PPQRICVHSH WTVCGQKMSK SLGNVVDPRT CLNRYTVDGF RYFLLRQGVP NWDCDYYDEK VVKLLNSELA DALGGLLNRC TAKRINPSET YPAFCTTCFP SEPGLVGPSV RAQAEDYALV SAVATLPKQV ADHYDNFRIY KALEAVSSCV RQTNGFVQRH APWKLNWESP VDAPWLGTVL HVALECLRVF GTLLQPVTPS LADKLLSRLG VSASERSLGE LYFLPRFYGH PCPFEGRRLG PETGLLFPRL DQSRTWLVKA HRT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Novel, compound heterozygous, single-nucleotide variants in MARS2 associated with developmental delay, poor growth, and sensorineural hearing loss PMID: 25754315
2. MARS2 is mutated in Autosomal Recessive Spastic Ataxia with Leukoencephalopathy patients. PMID: 22448145
3. Sequence analysis of mitochondrial MetRS indicates that this protein contains consensus motifs characteristic of class I aminoacyl-tRNA synthetase but lacks Zn2+ binding motif and C-terminal dimerization region found in MetRSs from various organisms. PMID: 15274629
相關疾病：

Spastic ataxia 3, autosomal recessive (SPAX3); Combined oxidative phosphorylation deficiency 25 (COXPD25)
亞細胞定位：

Mitochondrion matrix.
蛋白家族：

Class-I aminoacyl-tRNA synthetase family
數據庫鏈接：

HGNC: 25133

OMIM: 609728

KEGG: hsa:92935

STRING: 9606.ENSP00000282276

UniGene: Hs.744330