Recombinant Human Leucine-rich repeat-containing protein 17 (LRRC17)

中文名稱：

人LRRC17重組蛋白
貨號：

CSB-YP818720HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人LRRC17重組蛋白
貨號：

CSB-EP818720HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人LRRC17重組蛋白
貨號：

CSB-EP818720HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LRRC17重組蛋白
貨號：

CSB-BP818720HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人LRRC17重組蛋白
貨號：

CSB-MP818720HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LRRC17
Uniprot No.：

Q8N6Y2
別名：

LRRC17; P37NB; UNQ3076/PRO9909; Leucine-rich repeat-containing protein 17; p37NB
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

19-441
氨基酸序列

RK ASPGSVRSRV NHGRAGGGRR GSNPVKRYAP GLPCDVYTYL HEKYLDCQER KLVYVLPGWP QDLLHMLLAR NKIRTLKNNM FSKFKKLKSL DLQQNEISKI ESEAFFGLNK LTTLLLQHNQ IKVLTEEVFI YTPLLSYLRL YDNPWHCTCE IETLISMLQI PRNRNLGNYA KCESPQEQKN KKLRQIKSEQ LCNEEEKEQL DPKPQVSGRP PVIKPEVDST FCHNYVFPIQ TLDCKRKELK KVPNNIPPDI VKLDLSYNKI NQLRPKEFED VHELKKLNLS SNGIEFIDPA AFLGLTHLEE LDLSNNSLQN FDYGVLEDLY FLKLLWLRDN PWRCDYNIHY LYYWLKHHYN VHFNGLECKT PEEYKGWSVG KYIRSYYEEC PKDKLPAYPE SFDQDTEDDE WEKKHRDHTA KKQSVIITIV G
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors.
基因功能參考文獻：
1. low circulating plasma level of LRRc17 might serve as an independent and additive risk factor for osteoporotic fractures. PMID: 27355564
2. Whole-genome microarray mRNA-expression profiles of myofibroblasts and skin fibroblasts revealed four additional genes that are significantly differentially expressed in these two cell types: NKX2-3 and LRRC17 in myofibroblasts and SHOX2 and TBX5 in skin fibroblasts PMID: 27036009
亞細胞定位：

Secreted, extracellular space.
組織特異性：

Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells
數據庫鏈接：

HGNC: 16895

KEGG: hsa:10234

STRING: 9606.ENSP00000344242

UniGene: Hs.567412