Recombinant Human La-related protein 4B (LARP4B)

中文名稱：

人LARP4B重組蛋白
貨號：

CSB-YP821686HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人LARP4B重組蛋白
貨號：

CSB-EP821686HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人LARP4B重組蛋白
貨號：

CSB-EP821686HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LARP4B重組蛋白
貨號：

CSB-BP821686HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人LARP4B重組蛋白
貨號：

CSB-MP821686HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LARP4B
Uniprot No.：

Q92615
別名：

A630096F19; AI256361; D13Wsu64e; KIAA0217; La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La-related protein 4B; La-related protein 5; LAR4B_HUMAN; Larp4b; LARP5; MGC78318
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-738
氨基酸序列

MTSDQDAKVV AEPQTQRVQE GKDSAHLMNG PISQTTSQTS SIPPLSQVPA TKVSELNPNA EVWGAPVLHL EASSAADGVS AAWEEVAGHH ADRGPQGSDA NGDGDQGHEN AALPDPQESD PADMNALALG PSEYDSLPEN SETGGNESQP DSQEDPREVL KKTLEFCLSR ENLASDMYLI SQMDSDQYVP ITTVANLDHI KKLSTDVDLI VEVLRSLPLV QVDEKGEKVR PNQNRCIVIL REISESTPVE EVEALFKGDN LPKFINCEFA YNDNWFITFE TEADAQQAYK YLREEVKTFQ GKPIKARIKA KAIAINTFLP KNGFRPLDVS LYAQQRYATS FYFPPMYSPQ QQFPLYSLIT PQTWSATHSY LDPPLVTPFP NTGFINGFTS PAFKPAASPL TSLRQYPPRS RNPSKSHLRH AIPSAERGPG LLESPSIFNF TADRLINGVR SPQTRQAGQT RTRIQNPSAY AKREAGPGRV EPGSLESSPG LGRGRKNSFG YRKKREEKFT SSQTQSPTPP KPPSPSFELG LSSFPPLPGA AGNLKTEDLF ENRLSSLIIG PSKERTLSAD ASVNTLPVVV SREPSVPASC AVSATYERSP SPAHLPDDPK VAEKQRETHS VDRLPSALTA TACKSVQVNG AATELRKPSY AEICQRTSKE PPSSPLQPQK EQKPNTVGCG KEEKKLAEPA ERYREPPALK STPGAPRDQR RPAGGRPSPS AMGKRLSREQ STPPKSPQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Stimulates mRNA translation.
基因功能參考文獻：
1. data provide strong evidence that LARP4B serves as a tumor-suppressor gene in glioma, encouraging further exploration of the RNA targets potentially involved in LARP4B-mediatd growth inhibition PMID: 26933087
2. data identify LARP4B as a component of the mRNP code that influences the expression of its mRNA targets by affecting their stability PMID: 26001795
3. demonstrate that LARP4B plays an important role in the maintenance of LSCs and suggest that LARP4B may regulate the cell cycle of LSCs via suppressing the expression of cell cycle inhibitors PMID: 25534202
亞細胞定位：

Cytoplasm, cytosol.
數據庫鏈接：

HGNC: 28987

OMIM: 616513

KEGG: hsa:23185

STRING: 9606.ENSP00000326128

UniGene: Hs.159069